19.04.2025

Mexidol and Picamilon, the choice of drug

Quite often, doctors prescribe both drugs at the same time, since they combine perfectly with each other. This allows you to achieve a faster and more comprehensive effect in therapy. Drugs do not form toxic compounds in the body, since they are compatible in structure, although they differ in the mechanism of action.

Various disorders in the functioning of the central nervous system and the brain are more and more common in recent years. Contribute to this nerve congestion, a busy schedule, a genetic predisposition, bad habits.

In addition to these factors, organic pathologies lead to a malfunction in the work of the most important body systems .

All this extremely negatively affects the state of the body as a whole, worsens the quality of human life.

Currently, the pharmacological market provides many medications that can help the brain and nervous system cope with impaired activity.

These medicines include Mexidol and Picamilon.

“Mexidol”: characteristics of the drug

Mexidol is a domestic antioxidant and membrane protective agent.

Its main task is to prevent hypoxia of brain tissues, improve cerebral blood supply, normalize metabolic processes, and improve the processing of oxygen circulating in the body.

The main active ingredient is ethylmethylhydroxypyridine succinate.

The medication is released in the form of tablets, each of which contains 125 mg of the active ingredient and in ampoules containing an injection solution (2 ml and 5 ml).

Mexidol

Indications and contraindications

Application is indicated in the presence of pathologies and conditions such as:

  • Asthenia.
  • Withdrawal syndrome.
  • The consequences of a head injury.
  • Encephalopathies of various origins.
  • Myocardial infarction.
  • Cardiac ischemia (in complex therapy).
  • Neuroses and psychopathic conditions.
  • Decreased cognitive function due to atherosclerosis.
  • Intoxication with psychotropic substances.
  • VSD.
  • Post-stroke condition.
  • Alcohol poisoning.
  • Prevention of transient ischemic attack.
  • Panic attacks.
  • Open angle glaucoma.
  • Inadequate physical activity (as a means of preventing possible subsequent stress).

In surgery, the use of Mexidol is widely practiced in the conservative treatment of acute peritonitis and pancreatitis.

Contraindications for use are: acute functional disorders of the kidneys and liver. lactation period. pregnancy. individual intolerance to the drug. The drug is prohibited for children under 12 years of age.

Among the side effects can be observed: drowsiness, dizziness, dry mouth, skin rash, severe thirst.

pharmachologic effect

In the process of treatment, such therapeutic effects are manifested as:

  1. The disappearance of feelings of fear and anxiety.
  2. Platelet bonding slows down.
  3. The metabolic processes in ischemic zones of the myocardium are improved.
  4. Improves the electrical activity of the myocardium.
  5. Brain cells are more intensively supplied with oxygen.
  6. Sleep is stabilized.
  7. The body better resists the effects of negative factors.
  8. Improving memory and intelligence.

In addition, the drug improves brain activity, and also has an anticonvulsant and sedative effect. It is also known for its ability to lower the level of “bad” cholesterol in the blood.

“Picamilon”: characteristics of the drug

“Picamilon” is a drug from the group of nootropics. It is considered the first domestic nootropic drug.

Its main purpose is to influence the higher mental and metabolic processes in the brain. Also, due to the strong vasodilating (vasodilating) effect, it improves blood circulation and strengthens brain tissue.

The main active substance is nicotinoyl-gamma-aminobutyric acid.

The manufacturer provides two dosage forms of the drug – ampoules with a solution for intravenous or intramuscular administration. tablets containing 10 mg, 20 mg or 50 mg of the active ingredient.

Picamilon

Indications and contraindications

The situations in which the appointment is shown are:

  • TBI.
  • Neuroinfection.
  • Alcohol withdrawal.
  • Ischemic stroke (moderate or mild).
  • Treatment and prevention of migraine attacks.
  • Various neurotic pathologies (depression, phobia, neurosis, etc.).
  • Cerebrovascular insufficiency.
  • Memory impairment.
  • Senile psychosis.
  • Decrease in mental functions.
  • Open-angle glaucoma.
  • Pathology of the retina.
  • Chronic alcohol addiction.
  • Chronic fatigue.
  • Cochlear neuritis.
  • Recovery after heavy sports, physical or mental work.

In addition, Picamilon is used in urological practice. It is recommended for children starting from the age of 3, and adult patients suffering from various disorders of urination as a means of reducing hypoxia of the tissues of the bladder.

Contraindications to the appointment are: hypersensitivity to the components. renal pathology. stage of breastfeeding. pregnancy. ONMK.

The official instruction prohibits prescribing medication for children under 3 years old, and in the form of injections – for up to 14 years.

Side effects are expressed in headache, agitation. anxiety, nausea, skin rash and itching, dizziness, hypotension.

pharmachologic effect

Course treatment contributes to:

  • Stabilization of patients with speech and motor disorders.
  • Headache reduction.
  • Improve sleep.
  • Memory strengthening.
  • Improving mental and physical performance.
  • Establishment of metabolic processes in the brain tissues.
  • Protect brain cells from the harmful effects of free radicals.
  • Improving blood circulation in the brain.
  • Decreased vascular resistance, resulting in improved microcirculation.

Also, due to its tranquilizing effect, the medication is able to relieve patients’ feelings of unmotivated fear and tension.

What are the similarities of drugs

Both medicines are synthesized and produced in Russia. They are produced both in ampoule and tablet form. In the list of indications there are diseases in which both drugs are prescribed (TBI, asthenia, ischemic stroke, etc.). There are similarities in contraindications. Both that, and another can act as oxidants. But this, perhaps, is all that can be said about their similarities. The differences between them are much greater.

What is the difference between drugs

Medications differ in the following parameters:

  1. Belong to various pharmacological groups. Mexidol is an antioxidant, Picamilon is a nootropic.
  2. They differ in the chemical composition of the active substances.
  3. They have a different effect. The first – stabilizes cellular metabolism, the second – improves blood flow, dilating blood vessels.
  4. “Picamilon” can be given to children from 3 years old, a second medication – from 12 years.
  5. “Mexidol” can be used for acute alcohol poisoning, where the second remedy does not give a pronounced effect.
  6. “Picamilon” is able to reduce intracranial pressure. Another drug does not have this effect.
  7. “Mexidol” does not have pronounced tranquilizing properties, which are endowed with the second drug.

Drugs differ in cost. “Mexidol” in tablets costs from 233 to 499 rubles, ampoules – from 470 to 680 rubles. Picamilon tablets will cost 90-120 rubles, a solution for injection – from 60 to 130 rubles.

Mexidol and Picamilon

Which is better to choose

Which drug is better is hard to say. They are different in both farm groups and effects.

But, for example, hypotonics, it is better to refrain from taking “Picamilon” due to its pronounced effect of vasodilation.

Also, it should not be taken by people using the car and those whose activities require a quick psychomotor reaction. This is due to the sedative property of the drug.

People suffering from alcohol addiction are more likely to use Mexidol with its ability to quickly remove ethanol decay products from the body.

In addition, it relieves depression well.

In addition, when choosing, it is necessary to clearly understand what effect the patient expects from the reception of these funds.

With impaired functional nature, Mexidol will perfectly cope due to its powerful antioxidant effect. If there is a disease of an organic nature, here “Picamilon” should be preferred.

But it would be most reasonable to rely on the competence of the doctor, and entrust him with the choice of the drug.

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