Neither Vikasol nor Ditsinon are a panacea for all types of hemostatic pathologies. Vikasol acts as an emergency aid on the immediate cause of the violation. The use of the drug is not more than 4 days. Dicinon is used in the treatment for a long time, both in combination with other drugs, and for the prevention of bleeding.
In addition, the price of Vikasol is several times lower than the price of an analogue. In the absence of contraindications for use in treatment, if the diagnosis of the disease allows the use of this drug, then it is better to choose Vikasol.
When stopping bleeding of various etiologies and intensities, Vikasol and Dicinon are used. In order to more effectively stop hemostasis, you need to know not only the causes of the pathology, but also choose the hemostatic agent correctly.
Vikasol
Domestic drug Vikasol is an artificial analogue of vitamin K, belongs to the group of hemostatic and coagulants. With hemostatic properties, it is used to stop bleeding and bleeding, acts on liver cells, stimulating the production of prothrombin, which contributes to blood coagulation.
The active substance of the drug is menadione sodium bisulfite. One tablet contains 15 mg of this component. The white tablets are packaged in blisters of 10 pieces or packaged in glass containers of 30 pieces. 3 blisters are sold through the pharmacy network or a glass jar in a cardboard box, with enclosed instructions for use.
Ampoules with a solution of the drug contain 10 mg / ml of the active substance, intended for intramuscular administration. Ampoules are placed in contour cells of 5 pieces; they are packed in 2 packages in a cardboard box.
Vikasol is prescribed by prescription. The expiration date should be specified in the instructions for use. The price for a standard package of medicine is 20-80 rubles.
Dicinon
On the pharmacological market of the Russian Federation comes the drug Dicinon produced in Switzerland and Slovenia. Hemostatic, antihemorrhagic, angioprotective properties of this drug allow its effective use in stopping bleeding and bleeding.
The mechanism of action of the drug is due not only to an increase in the rate of formation of the primary thrombus, activation of the synthesis of thromboplastin, which helps to stop bleeding, but also to improve blood microcirculation, strengthen the vascular walls, and reduce their permeability.
An important factor in the use of the drug is the fact that it does not contribute to the formation of blood clots and narrowing of blood vessels, increases platelet activity.
A medicine is available in the form of a tablet and a solution for intravenous and intramuscular injections. The active component of dicinone is ethamylate. Its concentration in one white tablet is 250 mg. Excipients play a form-forming role. It is sold in a package of 100 pieces.
The ampoule with a solution for intravenous and intramuscular administration contains 125 mg / ml ethamylate. Sold in a package of 50 ampoules.
Shelf life is 5 years. The price for a standard package of tablets is from 350 rubles ; ampoules – from 550 rubles.
When and for whom are hemostatic drugs used
Hemostatic drugs are used for the treatment and prevention of the following diseases and pathologies:
- Bleeding in the acute stage of liver disease, septic conditions, pulmonary tuberculosis, intestinal pathologies.
- Hemorrhages with violation of the walls of blood vessels in diabetic angiopathy.
- Nasal, hemorrhoidal, uterine bleeding, retinal hemorrhages.
- Blood coagulation disorders when taking certain medications.
- Prevention and elimination of bleeding during various operations, radiation sickness, and injuries.
- Hemorrhagic disease.
- Heavy menstrual bleeding in women.
- Hemorrhagic disease of the newborn.
Application and dosage of Vikasol
Oral administration of the drug is prescribed for adults, 2-4 tablets per day, divided into 2-3 doses. Before surgery, if necessary, prescribe medication for 2-3 days.
Children: 3-4 years – 8 mg / day.; 5-9 years – 10 mg / day.; 10-14 years – 15 mg / day.
With the introduction of / muscle daily dosage for adults is 30 mg, with a treatment duration of 3-4 days. A repetition of the course of treatment is possible no earlier than 4 days later.
For newborns, the daily dose of the drug is up to 4 mg. Children up to a year are administered 2-5 mg / day.; up to 2 years – 6 mg / day. For children from 3 years of age, the administration of the drug in / muscle is carried out in the same dosage as when taking the tablets.
The drug is administered within 2-3 days before surgery.
Reception and doses of Ditsinon
The dose of the drug for adults inside is from 3 to 8 tablets per day, divided into 3-4 doses. The daily dose of the drug can be increased only in exceptional cases, after consulting a doctor.
Appointments to children are made based on body weight: 10-15 mg / kg – daily dose. It is necessary to divide it into several receptions. The doctor determines the duration of treatment.
In the period from the 5th day of the expected menstruation to the 5th day of the next menstrual cycle, women with menorrhagia are prescribed 3-5 tablets per day.
To exclude the risk of bleeding in the postoperative period, Dicinon is prescribed 1-2 tablets every 6 hours, until the threat is completely eliminated.
With intravenous / muscular and intravenous administration to adults, the dose is calculated in accordance with the patient’s body weight – 10-20 mg / kg, divided by the prescribed number of injections per day.
The daily dose for children is 10-15 mg / kg body weight, administered for 3-4 injections.
The duration of treatment is determined by the doctor.
For preoperative, postoperative injections, administration of the drug during surgery, its own doses have been developed.
In neotology, Dicinone treatment begins in the first 2 hours after the birth of a baby. 12.5 mg / kg of body weight of the newborn is administered per day .
Both drugs are contraindicated for patients with individual intolerance to their components. Vikasol is prohibited for patients with high blood viscosity, thrombophlebitis, vascular thromboembolism, while Dicinon can be prescribed for the treatment of such patients under the supervision of a doctor. Caution in the appointment is necessary for pregnant women in the first trimester.
You can not use Dicinon for diseases of porphyria and hemoblastosis. Vikasol is prescribed with caution, treatment is carried out under the supervision of a doctor during pregnancy, acute liver diseases and congenital deficiency of glucose-6-phosphate dihydrogenase.
Side effects with Dicinone: heartburn, lowering blood pressure, headaches, temporary decrease in leg sensitivity, redness of the skin of the body.
In the treatment of Vikasol, jaundice of the newborn may occur, hemolytic crisis in the newborn, hyperbilirubinemia.
The similarities and differences of hemostatic agents
The mechanism of action of hemostatic agents is different:
- Vikasol acts on the links of hemostasis by prothrombin synthesis;
- Dicinon normalizes platelet activity, improving microcirculation and strengthening the walls of blood vessels.
Vikasol is not able to cope with bleeding with hemophilia, Verlhof disease, von Willebrand disease. You must use another medicine. Whether Dicinon is suitable for this purpose, the doctor will decide. Drugs are prescribed after clarifying the causes of the pathology. These causes are determined using laboratory blood tests, diagnostic tests.
The correct prescription of a medicine to restore blood coagulation can only be done by the attending physician:
- Surgeon for injuries and surgical interventions.
- Gynecologist with uterine bleeding.
- Gastroenterologist with ulcerative bleeding.
- Hematologist for blood diseases.
- Other specialists in the treatment of diseases corresponding to their specificity.
Both tablets are not intended to stop acute venous and arterial bleeding. This is done with intravenous and / muscle injections. Tablets are effective in the prevention and treatment of chronic and periodic pathologies of hemostasis, not threatening the loss of a large volume of blood.
