Who should take the drugs Phenibut or Grandaxin should be determined by the attending physician. Phenibut is used for children from 8 years old, grandaxin from 18. For women in the premenstrual period and during menopause, grandaxin is appropriate, but it is not recommended for elderly people with atherosclerosis and glaucoma, but it can be done with cardialgia.
For insomnia, stuttering and convulsions, Phenibutum is suitable. Grandaxin has no hypnotic and sedative effect.
The modern rhythm of life is sometimes difficult for a person to withstand. He often gets tired, feels fear, anxiety, trouble. We have to resort to the help of drugs: tranquilizers, nootropics. They help relieve stress, anxiety, cheer up. Which ones are safe, have the least side effects, which is better, often interested in users.
Grandaxin
Grandaxin is a tranquilizer or benzodiazepine derivative. It is used to treat various nervous disorders, depression, and bad mood. Under its action, anxiety, fear decreases, obsessive thoughts pass. It is produced in 50 mg tablets , sold by prescription, the price is from 320 for 20 pcs., And from 700 for 60 pcs.
Act
The active substance of grandaxin is tofisopam, (the content in one tablet is 50 mg). The anxiolytic effect of the drug helps with autonomic disorders, relieves fear, anxiety, and stimulates activity. Drowsiness, lethargy during reception does not occur.
Indications
The spectrum of appointment of grandaxin is as follows:
- Vegetative dysfunctions.
- Mild depression.
- Cardiac pathologies on the background of a psychoemotional state.
- Climax, PMS (as a complex therapy).
- Difficulties in psychological adaptation.
- Muscular atrophy of a nervous nature.
- Lack of interest in life, decreased activity.
- Obsessive fear, anxiety.
- Hangover syndrome in patients with alcoholism.
Grandaxin is prescribed to people suffering from myopathy, myasthenia, when it is forbidden to use anxiolytics with the effect of relaxing muscles.
Limitations
Grandaxin is contraindicated in the following pathologies:
- Allergy to components.
- Increased aggression.
- Severe depression.
- Apnea Syndrome.
- Pulmonary insufficiency.
- Together with immunosuppressive drugs during transplantation (cyclosporine, sirolimus, tacrolimus).
- Lactose intolerance
- Chronic psychosis
- Phobia.
Grandaxin is excluded for pregnant women in the first trimester, breastfeeding, with epilepsy, atherosclerosis, closed glaucoma.
Dosage and administration
They recommend drinking the drug during the day, regardless of the meal. The doctor prescribes the dose and duration of treatment individually. For adults, usually 50-100 mg. (1-2 tablets), 1-3 times a day. Persons in advanced age and with renal pathology are two times less.
For children, the drug is indicated from 18 years old, pregnant women as directed. Breastfeeding is discontinued during treatment.
Side effects
When taking the medicine, side effects are not excluded:
- Loss of appetite.
- Dry mouth, nausea.
- Constipation, bloating.
- Headache, poor sleep.
- Seizures in individuals with epilepsy.
- Itchy skin.
- Pain and muscle tension.
- Labored breathing.
Due to excess doses, vomiting, respiratory depression, confusion, coma, and seizures in epileptics occur.
Interaction with others
The action of analgesics, sedatives, hypnotics, antidepressants increases with the use of grandaxin. Ethanol, barbiturates, nicotine, antiepileptic drugs reduce the concentration of tofisopam in the blood and weaken the effect of the tranquilizer. Reception with digoxin increases the therapeutic effect of cardiac glycoside. Antihypertensive agents increase the effectiveness of grandaxin. The drug is incompatible with alcohol.
Phenibut
Phenibut – a nootropic substance and anxiolytic, is a phenyl derivative of gamma-aminobutyric acid and phenylethylamine. Improves blood circulation and brain energy processes. Assign for the treatment of diseases associated with decreased attention, memory. It is released by prescription in 250 mg tablets, 100 mg powders are found. Price from 200 to 400 rubles.
Act
One tablet contains 0.25 g. Phenibut as an active substance and auxiliary components. Nootropic action improves attention, memory, brain activity. Phenylethymilan acts as a tranquilizer, relieves anxiety, eliminates anxiety, and sleep. Thus, the drug eliminates internal stress, anxiety, normalizes sleep, improves cerebral circulation, attention, memory, reduces problems with speech, movements.
Indications
Phenibut is prescribed for the following pathologies:
- Chronic fatigue syndrome.
- Obsessive and anxious conditions.
- Anxiety before surgical interventions, examination results.
- Prevention of motion sickness.
- Violation of the vestibular apparatus.
- Delayed outflow of urine with myelodysplasia.
- Nightmares, insomnia
- Excitation due to alcohol withdrawal.
- Traumatic brain injuries.
Phenibut is prescribed to improve memory, attention, increase physical, mental performance, in childhood with stuttering, tics, as a complex therapy for alcoholism.
Limitations
In some cases, taking the drug is contraindicated:
- Intolerance to some components in the composition.
- Liver disease.
- Erosion, gastrointestinal ulcers.
- The first trimester of pregnancy.
- Lactation period.
- Children under eight years old.
With an ulcer, gastrointestinal erosion, and liver pathology, use with caution.
Dosage and administration
The duration and dose of the drug is prescribed by the doctor. You need to drink tablets after eating three times a day for a course of two to three weeks. Swallowed whole, chewing, not chopping, with a glass of water. For adults, the dose is 250-500 mg, it is prescribed by the doctor, taking into account the diagnosis and age group. Phenibut has low toxicity, mild effect, it is prescribed for children from 8 years old, in some cases less than eight. Better for children powder form.
Side effects
Side effects of the drug are rare, in patients the following are possible:
- Nausea.
- Allergy.
- Increased anxiety
- Increased irritability.
- Sleep disturbance.
- Headache.
When they appear, you need to stop taking. In case of an overdose, there is: a decrease in blood pressure, impaired renal function, drowsiness, and vomiting.
Interaction with others
Phenibut combined with psychotropic, it increases the effect of sleeping pills, drugs, anticonvulsants, antipsychotics. The effect of alcohol when taken with phenibut is greatly enhanced.
General
Both drugs have anxiolytic effect – reduce anxiety, anxiety, fear, emotional stress, relieve obsessive thoughts, suspiciousness. They are prescribed for nervous and mental disorders, as a complex therapy for alcoholism. It is better to apply together, they reinforce each other’s action. The average price is the same; they are sold according to a prescription.
Difference
Medicinal substances belong to different pharmacological groups, they are of different composition, slightly differ in contraindications and side effects.
Phenibut is taken for coordination disorder, motion sickness, given to children. It calms the nervous system, increases the efficiency of the brain, is prescribed for atherosclerosis, memory impairment. The medicine can be addictive. Therefore, the dosage should be reduced gradually.
Grandaxinum is a more narrowly targeted drug, it is not addictive. In addition to the calming effect, it is effective for weakness, lethargy and muscle damage, heart pathology. Accepted during the day, it does not contribute to drowsiness.
