27.10.2020

Terbinafine or Clotrimazole, which is more effective

Both medicines are equally effective against fungus, and each of them has its own characteristics.

“Terbinafine” in tablet form is prescribed for systemic lesions of the body, deep mycoses, sometimes as an additional remedy for candidiasis (thrush). In the form of external products, “Terbinafine” is used to treat onychomycosis and fungal infections of the nails.

“Clotrimazole” is more effective against Candida fungi that cause thrush. Therefore, with this disease, it is better to use it. Also, this tool should be used for bacterial diseases of the genital organs and trichomonas vaginitis.

It is better for pregnant women to use the first medication, since it is allowed according to strict indications in all periods of pregnancy. “Clotrimazole” is contraindicated in the first trimester.

Those who have lactose intolerance, lactase deficiency, glucose-galactose malabsorption, are contraindicated in taking “Terbinafine” tablets, since they contain lactose.

As for the cost of drugs, it is approximately the same. Creams, spray and solution for external use are in the range of 200-220 rubles, tablets “Terbinafine” – 250 rubles. Also in pharmacies there is a medicine of Israeli production “Terbinafin-teva”, which costs much more.

The medication should be prescribed only by a doctor, based on the results of the tests. Self-medication can lead to complications and the further spread of the fungus.

For the treatment of fungus, many use folk remedies that only relieve the symptoms of the disease, but do not fight the pathogen. Therefore, you can not do without medications aimed at the destruction of microorganisms and the removal of symptoms of the disease. The article describes and compares the two most popular antifungal drugs.

Terbinafine

Antifungal agent. It has a pronounced fungicidal (in relation to dermatophytes, yeast, mold and some dimorphic fungi) and fungistatic (in relation to some yeast fungi).

Terbinafine

The active substance of the drug inhibits the synthesis of biologically active substances in the cell of the fungus, which entails a violation of biochemical processes and the death of microorganisms. When administered in tablet form, high concentrations of the drug accumulate in the skin, hair and nail plates, which ensures a fungicidal effect.

Active substance: terbinafine .

Release form: tablets, ointment, cream, spray.

Indications for use:

  • Mycosis of the scalp.
  • Fungal lesions of the skin and nails (onychomycosis).
  • Extensive dermatomycosis of smooth skin of the trunk and limbs.
  • Candidiasis.

Contraindications:

  • Hypersensitivity to the components of the drug.
  • Chronic and acute liver diseases.
  • Chronic renal failure.
  • Age less than 3 years; body weight less than 20 kg (for tablets).
  • Lactation period.
  • Lactose intolerance, lactase deficiency, glucose-galactose malabsorption (for tablets).

During pregnancy, the drug can be used only with strict indications.

It is made in Russia. Released by prescription.

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Clotrimazole

Antifungal agent. It has a pronounced antifungal, antibacterial, antiprotozoal, trichomonacid effect. It is active against some yeast, mold and dermatophytic fungi, as well as against certain bacteria.

Clotrimazole

The action is due to the destruction of the cell membrane of the fungus and the violation of biochemical processes, which causes the death of the microorganism.

Active substance: clotrimazole .

Release form: vaginal tablets, cream, ointment, solution for external use.

Indications for use:

For vaginal tablets:

  • Candidiasis.
  • Trichomonas vaginitis.
  • Prevention before gynecological procedures.
  • Remediation of the birth canal.

For cream, ointment and solution for external use:

  • Dermatomycosis.
  • Multi-colored lichen.
  • Erythrasma
  • Genital candidiasis.
  • Balanitis.

The tool can not be used with intolerance to the components and in the first trimester of pregnancy. In the II and III trimester, you can use the medication according to strict indications.

It is made in Great Britain and Poland. It is released without a prescription.

Comparison

Both drugs have an antifungal effect and destroy some types of dermatophytes, mold and yeast. They are used to treat candidiasis, mycosis, onychomycosis.

Comparison table:

Comparison criterion Terbinafine Clotrimazole
1. The active substance. Terbinafine. Clotrimazole.
2. Release form. Pills, cream, ointment, spray. Vaginal tablets, cream, ointment, solution for external application.
3.Action. Fungicidal and fungistatic (depending on the type of mushroom and the concentration of the active substance). Antifungal, antibacterial, antiprotozoal, trichomonacid.
4.How does it work? Suppresses the synthesis of biologically important substances in the fungal cell. Destroys the cell membrane of the fungus and disrupts the course of biochemical processes in the cell.
5. Contraindications Hypersensitivity to the components of the drug.
· Chronic and acute liver diseases.
· Chronic renal failure.
· Age less than 3 years; body weight less than 20 kg (for tablets).
· Lactation period.
· Lactose intolerance, lactase deficiency, glucose-galactose malabsorption (for tablet form).
· Intolerance to components.
· I trimester of pregnancy.
6. Vacation conditions On prescription. Without recipe.

Indications for use with the funds also vary. The first medication is used to treat exclusively fungal diseases of the skin and nails. And the second, as it has an antibacterial effect, is intended not only to eliminate fungal infections, but also to treat bacterial diseases of the genital organs (balanitis, etc.).

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