24.11.2020

Cavinton

Headaches caused by spasm of the vessels of the head, poor memory, lack of mental performance, blurry vision, ringing in the ears these problems, hitherto considered almost exclusively the old, can now face any person. To solve them often helps Cavinton – popular product from the group of nootropic drugs. It is often used when problems with the cerebral circulation, hypoxia of the brain tissue, traumatic brain injuries.

Description

The active substance of Cavinton – Vinpocetine. It is a plant alkaloid derived from the flower called periwinkle. The therapeutic properties of this plant have long been known in folk medicine.

Vinpocetine belongs to the class of nootropic drugs that is, drugs that affect the brain. It has cerebrovasculature and cerebroprotective effect. The main effects of Vinpocetine – improve metabolism and blood circulation in the nervous tissue, antioxidant activity. Also, the drug improves blood properties.

Among the demonstrated a drug’s metabolic effects, the following should be noted:

  • the decrease of the degree of damage caused by amino acids
  • inhibition of the action of sodium and calcium channels,
  • stimulation of the neuroprotective effect of chlorpromazine
  • improving the consumption and metabolism of glucose and oxygen,
  • stimulation of the metabolism of serotonin and norepinephrine
  • increasing the concentration of the energy molecule ATP in the brain tissue,
  • the increasing resistance of nervous cells to hypoxia.

Effects associated with improve blood circulation:

  • reduced resistance of cerebral vessels,
  • reducing the tendency of platelet aggregation,
  • reduction of pathological blood viscosity,
  • increasing the deformability of red blood cells,
  • blocking the uptake of adenosine by erythrocytes
  • impact of oxygen by erythrocytes
  • optimize blood circulation in small capillaries (microcirculation) .

The drug has no significant effect on systemic blood flow without changing blood pressure, heart rate.

An important feature of the drug is that it is most active in the affected ischemic pathology of the brain.

The drug readily crosses the blood-brain barrier, which explains its nootropic effect. It is absorbed in the intestines within one hour. Two-fifths of the drug is excreted through the intestines, and three fifths through the kidneys.

Testimony

The main areas of medicine that use the drug:

  • neurology,
  • neuropathology,
  • psychiatry,
  • ophthalmology,
  • otolaryngology,
  • traumatology.

The main purpose of Cavinton is the treatment of various diseases and syndromes, directly or indirectly associated with lack of cerebral circulation.

Cavinton can be prescribed by doctors for:

  • transient ischemic attacks;
  • atherosclerosis;
  • vascular dementia;
  • progressive stroke;
  • recovering from a stroke, toxic or hypertensive encephalopathy;
  • cervical degenerative disc disease complicated disorders of cerebral circulation;
  • neurological and mental disorders caused by cerebrovascular disorders;
  • motor disorders;
  • the memory impairment.

Also Cavinton is often used in the recovery after traumatic brain injury.

Ophthalmic the drug is used for:

  • spasm of the retinal vessels,
  • atherosclerotic lesions of the ocular vessels
  • thrombosis and embolism of ocular vessels,
  • degenerative changes in the eye tissues,
  • secondary glaucoma.

In otolaryngological practice, the drug may be useful in the following cases:

  • hearing loss due to advanced age, heart failure or toxic injury of the tissues;
  • Meniere’s disease;
  • system dizziness;
  • vasovegetative disorders during menopause;
  • kohleovestibularnyi syndrome.
Contraindications

Cavinton is a relatively safe drug, and it can be applied even people in serious condition. Neither renal nor hepatic failure may not be a contraindication to taking the drug. You cannot take only in severe forms of ischemic heart disease and arrhythmias.

A relative contraindication is the children’s age (under 18). In practice, however, many pediatricians prescribe it to children, if there is no other alternative. However, to treat this drug children should not be, because only the doctor can find the necessary for a child the dose and form of the drug, taking into account the patient’s age and type of disease.

Use in pregnancy and lactation

The drug crosses the placental barrier, and its use during pregnancy is not recommended. Although it seems that the question in this case is small doses, but the risk is not worth it, because the safety of the drug for such cases is not proven. But experiments on animals showed that Vinpocetine may be the cause of premature miscarriage and placental bleeding. Also Vinpocetine is able to enter breast milk, so breastfeeding he is also prohibited.

Side effects

There is no drug at admission which would exclude side effects, Cavinton is no exception. The most common side effects while taking the drug are allergic reactions, primarily skin rash and itching. You might also encounter neurological responses – headaches, agitation, dizziness, insomnia or, conversely, drowsiness. When the pill may appear indigestion, nausea, diarrhea, heartburn. There may also be dryness of the mouth.

Quite rare are the effects associated with the cardiovascular system – tachycardia, arrhythmia, prolongation of the T wave on the ECG. More often unable to meet jump HELL.

Intravenous administration increases the risk of arrhythmias. Patients with hemorrhagic stroke, the drug can be used only in the case if you have passed the acute manifestations of the disease (5-7 days).

Release form

The main form of the drug are tablets. They are available in a dosage of 5 mg. there are Also tablets Cavinton Forte with a doubled dosage of 10 mg of Vinpocetine.

In addition, there is a solution for infusion, produced in ampoules. 1 ml of this solution contains 0.005 g of Vinpocetine. Ampoules solution have a volume of 2, 5 and 10 ml.

Usage instructions

In most cases it is recommended to take 5-10 mg 2-3 times a day. To start treatment is best with a dose of 5 mg Maximum daily dose is 30 mg.

Cavinton is a medicine long term effect and, consequently, the duration of the course can be a great 1-3 month. In some cases this time can be extended up to 8 months. The effect also begins to appear not immediately but after about a week, in some cases sooner and some later. In order to avoid withdrawal symptoms stop taking the drug, you must gradually, within three days of reducing the dose. In diseases of the kidneys and liver (except in severe forms), dose not require correction.

Take the tablets preferably after meals.

Instructions for use of the intravenous solution

The dosage for intravenous administration is determined by the physician based on the severity of the disease. Most often people take a daily dose of 20-25 mg (4-5 ml). This volume of the drug solution is diluted in 500 ml saline or dextrose solution. Prepared the volume of infusion fluid injected intravenously within 3 hours after cooking. The recommended rate of solution entering the blood 80 drops per minute. If the solution is well tolerated by the patient, the daily dose can be increased. The average daily dose is 0.65 mg/kg of body weight. This daily dosage should not exceed 1 mg/kg of body weight. The duration of treatment depends on the disease and condition of the patient, it is usually 10-14 days.

Intravenously and intramuscular injections are not recommended.

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2 thoughts on “Cavinton

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