Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting
The spectrum of somatic alterations in hematologic malignancies includes substitutions, insertions/deletions (indels), copy number alterations …
The spectrum of somatic alterations in hematologic malignancies includes substitutions, insertions/deletions (indels), copy number alterations …
Adoptive transfer of T cells genetically modified to express chimeric antigen receptors (CARs) targeting CD19 …
B-cell receptor kinase inhibitor (KI) therapy represents a paradigm shift in chronic lymphocytic leukemia (CLL) …
Primary central nervous system lymphomas (PCNSLs) and primary testicular lymphomas (PTLs) are extranodal large B-cell …
Minimal residual disease (MRD) is highly prognostic in pediatric B-precursor acute lymphoblastic leukemia (B-ALL). In …
The efficacy and favorable safety profile of daratumumab monotherapy in multiple myeloma (MM) was previously …
Talin is an integrin adaptor, which controls integrin activity in all hematopoietic cells. How intracellular …
Chronic lymphocytic leukemia (CLL) is the most prevalent leukemia affecting adults and remains an incurable …
The pathogenesis of mycosis fungoides (MF), the most common cutaneous T-cell lymphoma (CTCL), is unknown. …
Idelalisib is a small-molecule inhibitor of PI3Kδ with demonstrated efficacy for the treatment of relapsed/refractory …
Platelets protect vascular integrity during inflammation. Recent evidence suggests that this action is independent of …
Programmed cell death ligand 1 (PD-L1) is expressed on both select diffuse large B-cell lymphoma …
We performed targeted next-generation sequencing (NGS) of DNA samples from bone marrow or peripheral blood …
Therapies with novel mechanisms of action are needed for multiple myeloma (MM). B-cell maturation antigen …
Recurrent somatic mutations of the calreticulin (CALR) gene were previously reported in a subset of …