24.10.2020

Anaprilin and enalapril, drug choice

Both drugs should be taken only as directed by a doctor. Only he can determine what is best in one case or another.

However, if the patient is pregnant or breastfeeding, Anaprilin should be chosen. The same drug is recommended for children, since the use of enalapril in such cases is strictly prohibited. In an adverse case, this can lead to various fetal pathologies. Also, enalapril should be excluded for people who have elevated levels of potassium in the body.

If the patient requires a long hypotensive effect, then enalapril, which is effective for 24 hours, should be chosen. Anaprilin, unlike its counterpart, has a fairly short action and is excreted by the kidneys after 3-5 hours.

Thus, both drugs are effective against the fight against hypertension. However, each has its own advantages and disadvantages. Therefore, a specific drug should be determined by the doctor individually for each patient, so as not to harm health.

Elevated pressure significantly increases the load on the myocardium. This contributes to the development of a heart attack , which can lead to death. With arterial hypertension, doctors prescribe antihypertensive drugs of various pharmacological groups. They can be included as part of complex therapy, or taken separately.

Quite often, Anaprilin and Enalapril are prescribed. Many patients think that these are two identical drugs. However, this opinion is erroneous. To understand the difference, you need to consider them in more detail.

Anaprilin

Belongs to the group of beta-blockers . It has hypotensive, antianginal and antiarrhythmic effects. A single application can reduce blood pressure, but a persistent antihypertensive effect occurs 2 weeks after administration. The active substance is propranolol hydrochloride . One tablet includes 10 or 40 mg of active substance. When taken orally, about 90% of the drug is absorbed by the gastrointestinal tract.

Anaprilin

The drug is prescribed for the following pathologies:

  • Coronary artery disease.
  • Hypertonic disease.
  • Myocardial infarction.
  • Arrhythmia.
  • Tachycardia.
  • Pain in the sternum.
  • Tremor of the limbs.
  • Panic attacks.
  • Migraine.

For adults, taking the drug begins with 20 m . The maximum dose per day can reach 320 mg in 2-3 doses . Also, in medical institutions, they are injected intravenously slowly, at a dosage of 1 mg. After 2 minutes, the same dose is repeated. In the absence of effect, additional administration is possible. The maximum hypotensive effect is observed after 1.5 hours.

The drug can also be prescribed by a doctor to children from 1 month in a special dosage form. The initial dose is calculated from 1 mg / kg / day . For premature infants, the dosage is calculated individually.

The duration of treatment is 6 months . When discontinuing the drug, a gradual dose reduction is not required. If relapse occurs, a repeat test is required for a satisfactory reaction of the body.

Contraindications for taking Anaprilin are:

  1. Acute heart failure.
  2. Cardiogenic shock.
  3. Asthma.
  4. Acidosis.
  5. Atrioventricular block.
  6. Chronic liver disease.
  7. Diabetes.
  8. Low blood pressure.

During pregnancy, the use of the drug is possible only in extreme cases, if the potential harm to the fetus will be significantly less than the benefit to the mother. When used, careful monitoring of the fetus is required. Termination of admission should be carried out at least 48 hours before delivery.

When breastfeeding, Anaprilin is not recommended. The active substance is excreted in breast milk, which can cause harm to the fetus. In this case, monitoring the condition of the baby or stopping breastfeeding is required.

A urine sample for Sulkowice

Enalapril

It belongs to the group of ACE inhibitors. The active substance is enalapril . Depending on the dosage, the tablet may contain 2.5, 5, 10 and 20 mg of the active substance. About 60% of the drug is absorbed through the digestive tract. The onset of action occurs one hour after administration, and the maximum effect after 4-5 hours. Duration of action is 24 hours.

Enalapril

Indications for use are:

  • Hypertonic disease.
  • Chronic heart failure (when used together with other drugs).
  • Prevention of heart failure.
  • Prevention of coronary ischemia in patients with problems with the functioning of the left ventricle.

The average dose of 10-20 mg per day , in 2 divided doses. The maximum dose per day is 80 mg .

Contraindications are:

  1. Angioneurotic edema.
  2. Renal artery stenosis.
  3. Hyperkalemia
  4. Pregnancy.
  5. The period of breastfeeding.
  6. Children under 18 years old.
  7. Individual intolerance to constituent components.

When pregnancy occurs, the use of the drug should be stopped immediately. If there is a need to use the drug during lactation, then breast-feeding should be discontinued.

Similarities and differences

The main similarity of drugs is that they both have a hypotensive effect and are prescribed for hypertension. Despite the fact that they act the same way, they belong to different pharmacological groups.

Anaprilin has a clear advantage, since almost the entire drug is absorbed in the body. It can also be administered intravenously, which significantly reduces the time to reduce pressure than when taking tablets.

Both drugs in case of an overdose have a large number of side effects, among which there are:

  • Headache.
  • Allergic reactions.
  • Dizziness.
  • Nausea, vomiting.
  • Sleep disturbance.
  • Decreased potency and libido.

Also the difference is the duration of the therapeutic effect . Enalapril is a fairly powerful medicine compared to Anaprilin. However, the cost of this drug is much higher.

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