Ascoril and Stoptussin have different indications for use, so the doctor should decide which drug is better for the doctor individually, especially since a number of undesirable effects may develop during treatment.
The following adverse reactions may occur due to Ascoril treatment:
- Headache, vertigo.
- Excessive nervous irritability.
- Insomnia and drowsiness.
- Bronchospasm.
- A sharp drop in blood pressure.
- Trembling of certain parts of the body.
- Cramps.
- Diarrhea, nausea, vomiting.
- Tachycardia.
- Exacerbation of peptic ulcer.
- Urine staining
If therapeutic doses are exceeded, an increase in undesirable effects may be observed. In this case, Ascoril is canceled and symptomatic treatment is prescribed.
Due to the use of Stoptussin, the following side effects may occur:
- Headache, dizziness, drowsiness.
- Nausea, refusal to eat, abdominal pains, vomiting, loose stools, heaviness in the stomach, bitterness in the mouth, heartburn.
- Dyspnoea.
- Chest pain, increased heart rate, palpitations.
- The tides.
- Pain around the eyes.
- Urolithiasis
When taking the drug in high dosages, signs of poisoning may appear:
- Drowsiness.
- Nausea.
- Vomiting
The specific antidote is unknown, therefore symptomatic treatment is indicated.
The pharmaceutical industry offers a lot of drugs used to treat cough related diseases. Such drugs include Ascoril and Stoptussin. Let’s look at how these medicines differ.
Ascoril
Medication is available in tablets and syrup. As therapeutic substances, they contain salbutamol, bromhexine and guaifenesin.
The tablets are white, round in shape. They have a chamfer and risk.
They contain the following additional components:
- E216.
- E218.
- E576.
- E553b.
- E551.
- E1401.
- E383.
A syrup is a clear, orange liquid that has a specific odor.
They include:
- Sucrose.
- Flavors pineapple and blackcurrant.
- Sorbitol.
- E202.
- E104.
- Glycerol.
- Macrogol.
- E330.
- Levomenthol.
- Water.
- E211.
Ascoril has a bronchodilator, expectorant and mucolytic effect. The therapeutic effect of the medication is explained by its active components:
- Salbutamol refers to bronchodilators, it removes and prevents bronchospasm, increases VC. After oral administration, it is well absorbed from the digestive tract. Its bioavailability is 50%. Only up to 10% of the accepted dosage is combined with proteins. Salbutamol migrates through the placenta. In the liver and intestines, it undergoes metabolism. The half-life is 3.8-6 hours. Salbutamol is excreted from the body mainly through the kidneys.
- Bromhexine promotes sputum discharge. After oral administration, up to 99% of the active substance is absorbed within 30 minutes. Bromhexine has a low bioavailability due to the “first pass” effect through the liver. It easily passes through the blood-brain and placental barrier. In the liver, bromhexine is metabolized. It is excreted with urine, the half-life is 15 hours. In people with impaired renal function, bromhexine is excreted more slowly and can accumulate in the body.
- Guaifenesin belongs to mucolytics, helps sputum discharge, thanks to it a dry cough becomes wet. It is rapidly adsorbed from the digestive tract. Guaifenesin is metabolized in the liver. It is excreted from the body with sputum and urine for 2 hours.
Stoptussin
The drug is made in tablets and drops. Their main components are butamirate and guaifenesin.
Drops are a clear, viscous liquid. Its color may be yellow or tan.
Drops contain the following auxiliary components:
- Ethanol.
- Flower fragrance.
- Twin 80.
- Water.
- Macrogol.
- Licorice.
The tablets are white or almost white, flat-cylindrical in shape, they have a chamfer and risk.
They include the following additional components:
- Aerosil.
- Mannitol.
- MCC.
- E576.
- Glyceryl tribhenate.
Butamirate acts on the cough center, which is located in the brain, resulting in suppression of coughing.
Guaifenesin promotes sputum discharge.
After oral administration, butamirate is completely adsorbed from the digestive tract. Up to 94% of the accepted dosage combines with proteins. Butamirate is metabolized in the liver. It is excreted mainly with urine, the half-life is 6 hours.
What are they like
Ascoril and Stoptussin have the following similarities:
- At the time of their administration, it is recommended to interrupt breastfeeding.
- Medicines should be used with caution by motorists.
- Drugs can not be used with intolerance to their composition, in which case they can provoke an allergy.
- Ascoril and Stoptussin tablets should be stored at temperatures up to 25 degrees. Drops of Stoptussin do not lose their effect at a temperature of 10 to 25 degrees.
Comparison and which is better
Ascoril and Stoptussin have many differences:
| Ascoril | Stoptussin | |
| Indications for use | The medicine is used for wet cough, which is accompanied by thick, viscous, difficult to separate sputum. | The drug is used to suppress a dry, unproductive cough. |
| Release form | Syrup, tablets. | Drops, pills. |
| Pediatric Use | In syrup, it is possible from birth, in tablets from 6 years. | Drops are allowed from 6 months, tablets from 12 years. |
| Use during pregnancy | It is forbidden. | It is forbidden in the first trimester, at later dates it can be used with caution. |
| Shelf life | 24 months. | 5 years. |
| Sale Rules | On prescription. | Over the counter. |
| Contraindications | Pathologies of the liver, heart and kidneys, gastrointestinal ulcer and bleeding from its departments, glaucoma, hyperthyroidism, diabetes mellitus in the stage of decompensation. Tablets should not be drunk at high pressure. | Myasthenia gravis |
