27.10.2020

Ascoril or ACC, drug choice

Ascoril should be taken by people, starting from the first days of the disease with exacerbation of bronchial asthma and bronchitis, bronchiolitis in children from 1 year old, with SARS. Children should be given medicine in the form of syrup taking into account the age norm, and for adults in the form of tablets, 1 pc. three times a day for 7 days. It should be taken in the treatment of antibiotics such as erythromycin and cephalexin, it enhances their effectiveness.

Ascoril should not be treated by persons with hepatic and renal failure, with an unstable sugar level against the background of diabetes mellitus. It is better to choose another remedy and for those suffering from glaucoma, salbutmol, acting on the receptors of the eye, can cause a sharp increase in intraocular pressure. With caution and only with the consent of the attending physician, you can drink Ascoril with the use of hormones of the adrenal glands and diuretics.

ACC should be used for exacerbation of chronic bronchitis, bronchiectasis, with pneumonia, lung abscess. The dosage can be both 200 mg 3 times a day, and 600 mg once for 7-10 days. 100 mg 3 times a day can be used for chronic obstructive bronchitis, bronchiectasis as a prophylactic agent for a long time. It negatively affects the digestibility of antibiotics by the body, so the interval between them should be at least two hours. It is better to refuse ACC if there is a peptic ulcer of the stomach and duodenum, lactose intolerance.

In the autumn-winter period there is a peak incidence of various respiratory diseases. This can be either a usual ARVI or an exacerbation of a previously existing chronic pathology. All these diseases have a common symptom – cough. The most effective in recent years are Ascoril and ACC, this article will help to figure out which is better to use depending on the situation.

What is Ascoril

This drug is a combination of three substances – salbutamol , guaifesin and bromhexine . Available in the form of tablets (in a pack of 10, 20 and 50 pieces) and syrup (100 ml), the latter can be taken also for children from 1 year old.

Ascoril

All components of the drug perfectly complement and enhance the effect of each other. Ascoril is rapidly absorbed into the blood from the gastrointestinal tract and is completely excreted from the body only three days after administration. Its main actions are:

  1. Reduces sputum viscosity . Bromhexine and guaifezin make the separated mucus more liquid and increase its volume, which facilitates the discharge of sputum.
  2. Enhances expectoration . The above substances act on the epithelium of the bronchi, causing the lungs to cleanse.
  3. Expands the bronchi . This is achieved due to the fact that salbutamol acts on receptors in the smooth muscles of the bronchi, causing them to become wider. It also improves blood circulation in the lungs, which, coupled with the expansion of the bronchi, increases the vital capacity of the lungs, that is, the amount of air that a person can inhale.

Indications for use are: acute and chronic bronchitis; bronchial asthma; cystic fibrosis; pulmonary tuberculosis; tracheobronchitis; whooping cough; pneumonia; obstructive bronchitis; pneumoconiosis.

Contraindications include an allergic reaction to any component of the drug, infancy, pregnancy and the period of breastfeeding (Ascoril crosses the placental barrier, easily passes into breast milk). Also, the medicine is not prescribed for serious cardiac arrhythmias, myocardial inflammation, uncontrollable hypertension, narrowing of the aortic valve. More harm than good can be caused by taking the drug against hyperthyroidism, diabetes mellitus, glaucoma, acute gastrointestinal ulcer, and liver and kidney failure.

Multislice computed tomography (CT) of the kidneys

What is the “ACC”

ACC is an expectorant drug . It liquefies sputum with the help of its active substance, acetylcysteine. This tool does not lose its effectiveness even in the case of purulent sputum. Another positive property is the antioxidant effect of the drug. It is noted that regular prophylactic administration of ACC significantly reduces the frequency and severity of exacerbations in people suffering from cystic fibrosis and chronic obstructive bronchitis.

"ACC"

The medicine is produced in the form of effervescent soluble tablets of 200 mg or powder in a sachet of 600 mg . In the latter case, the drug will be called ACC Long and is taken once a day, since 600 mg is a daily dose. In pediatrics, ACC Long can be used in children from the age of 14, and conventional tablets from 2 years.

Indications for use are various forms of bronchitis, cystic fibrosis, tracheitis, lung abscess, pneumonia, bronchiectasis. As well as acute and chronic sinusitis, otitis media.

Contraindications include: ulcerative processes in the gastrointestinal tract during exacerbation, bleeding, lactose intolerance and lactase deficiency (lactose is contained in the preparation as an auxiliary substance), pregnancy and the period of breastfeeding, children under two years of age, and individual intolerance to acetylcysteine.
What is common between drugs

Despite the different composition, these two cough remedies have much in common, namely:

  • They have a pronounced expectorant effect due to liquefaction of sputum.
  • They are used to treat the same diseases (bronchitis, bronchial asthma, cystic fibrosis).
  • They have several forms of release and can be used to treat children.
  • They are prescription drugs, that is, for their purchase in a pharmacy, you must provide a prescription from your doctor.
  • They have approximately the same cost on average about 300 rubles.
  • Contraindicated for use during pregnancy and lactation, as well as for bleeding and exacerbations of gastric ulcer, duodenal ulcer and other intestines.
What are the differences between Ascoril and ACC

Differences between these drugs are also available. As already described above, they have a different composition . Ascoril is a combination drug consisting of three drugs, and ACC is monocomponent. In this regard, they have a number of their features, namely:

  1. Ascoril has proven itself in the treatment of bronchitis with an asthmatic bias and in bronchial asthma itself due to salbutamol, which dilates the bronchi well and improves their blood supply, thereby increasing the volume of inhaled air, and over time contributes to a more rapid removal of pneumonia. It works better with inflammation of a non-purulent nature, with purulent sputum its effectiveness may decrease. Ascoril is used only for acute lung disease, it is ineffective in the treatment of sinus diseases. May adversely affect the condition of the liver and kidneys if their function is already reduced to failure.
  2. ACC has wider application. It is the drug of choice for chronic bronchitis, including obstructive, as well as pneumonia, bronchiectasis, lung abscess and cystic fibrosis. This is because its effectiveness does not decrease against the background of a purulent process. ENTs are also often used by ENT doctors as an additional tool for various kinds of sinusitis and otitis media. Due to its antioxidant effect, it acts as a prophylactic for various chronic lung pathologies, so it can be drunk without exacerbating the disease. At the same time, it is quite aggressive towards the mucous membrane of the stomach and duodenum, therefore, more often than Ascoril causes exacerbation of gastritis and ulcers.

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