31.10.2020

Gliatilin or Ceraxon, the choice of drug

Gliatilin and Ceraxon are not complete analogs, each nootropic has its own characteristics and the doctor should choose the treatment regimen, especially since these drugs are prescribed.

Gliatilin and Ceraxon are nootropics . These medicines are used to treat stroke, dementia, and head injuries. Let’s look at what these drugs have in common and how they differ.

Gliatilin

Gliatilin is on sale in capsules and injections, which contain choline alfoscerate as the main ingredient.

Gliatilin

Capsules are soft, gelatinous, opaque. They have an oval shape, if they are opened, then inside you can find a colorless thick liquid.

The solution for injection is a clear liquid, without color and odor.

Capsules contain the following formative ingredients:

  • Glycerol.
  • E172.
  • Water.
  • E216.
  • Titanium white.
  • E218.
  • Gelatin.
  • Ezitol.
  • E491.

Water is included in the solution for injection as an additional component.

Gliatilin is a central cholinomimetic. The medication contains choline, which is released from it when it enters the brain. Choline is involved in the synthesis of acetylcholine, the latter is one of the main neurotransmitters of excitation, which has a positive effect on the transmission of nerve impulses.

Alfoscerate is required for the formation of phosphatidylcholine – the main building material of the cell membrane, it is these substances that give its elasticity and improve the function of receptors.

Nootropic means improves memory, blood circulation and metabolism in the brain, accelerates the recovery of its cells after a trauma.

After oral administration, up to 88% of the drunk dosage is adsorbed. The drug easily migrates through the BBB, is deposited in the central nervous system, lungs and liver. It is secreted mainly in the form of carbon dioxide through the lungs, and is excreted in a small amount with urine and feces.

The drug does not violate the menstrual cycle, does not cause mutations and congenital malformations of the fetus.

It is recommended for the treatment of the following pathologies:

  1. An acute period after a head injury (the medication can be administered to people who have impaired consciousness and are in a coma).
  2. Multi-infarct dementia.
  3. Disorder of blood circulation in the brain.
  4. Behavioral and emotional changes: frequent mood swings, indifference to what is happening, nervousness, pseudomelancholy in patients of an older age group.
  5. Problems with speech and memory, weakening of the concentration of attention, which are provoked by natural aging or impaired cerebral circulation.

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Ceraxon

Ceraxon is available in the form of solutions for oral administration, intravenous and intramuscular administration. They as a medicinal component contains sodium citicoline .

Ceraxon

Injection solution contains hydrochloric acid and sodium hydroxide as additional ingredients. It is a clear, colorless liquid.

The oral solution as additional ingredients contains:

  • Sorbitol.
  • Glycerol.
  • E216.
  • E218.
  • Strawberry flavoring.
  • Water.
  • E331.
  • E954.
  • E202.
  • E330.

The oral solution is a clear, colorless liquid that smells like strawberries. In the cold, a small amount of crystals may form that do not affect the quality of the drug.

The drug refers to nootropics.

Citicoline is necessary for the formation of cell membrane components. In addition, he has the following actions:

  1. Recovers damaged cell membranes.
  2. It inhibits the activity of phospholipases that destroy cell membranes.
  3. Prevents the biosynthesis of free radicals.
  4. It affects apoptosis and prevents cell death.
  5. Reduces foci of brain tissue damage during stroke, restores cholinergic transmission.
  6. Reduces prolonged post-traumatic coma and recovery period, the severity of neurological symptoms after a head injury.
  7. It normalizes memory, increases concentration, improves self-care skills that are lost due to chronic oxygen starvation of brain tissue.

The drug is well absorbed regardless of the route of administration. Passing through the liver, it undergoes metabolism. The medication easily penetrates the brain. Only 15% of the dose is excreted from the body: about 12% through the lungs with carbon dioxide, the remainder with urine.

The medicine is prescribed in the presence of the following diagnoses:

  • Acute stage of ischemic stroke.
  • The rehabilitation period after hemorrhagic and ischemic stroke.
  • CNS injury, both in the acute and recovery period.
  • Violations of behavior, speech, memory caused by the aging of the body or vascular pathologies.
What are they like

Gliatilin and Ceraxon have the following similarities:

  1. Nootropic drugs have general indications for use.
  2. Both medicines are for adults only.
  3. Medicines are contraindicated in women who support breastfeeding.
  4. Both nootropics are not possible with intolerance to their composition, since they can cause an allergic reaction.
Comparison and differences

Gliatilin and Ceraxon have the following differences:

Gliatilin Ceraxon
Release form Injection and infusion solution, capsules. Solution for oral administration, solution for infusion and injection.
Manufacturer country Italy. Spain.
Use during pregnancy. Gliatilin is contraindicated in women in position. Ceraxon can be used during gestation.
Contraindications The medicine is not possible with severe vagotonia.
Side effects Nausea may occur due to medication. The drug can cause headaches, dizziness, sensation of heat, trembling of certain parts of the body, nausea, vomiting, diarrhea, hallucinations, edema, dyspnea, insomnia, impaired sensation, lack of appetite, agitation, liver dysfunction. During therapy, the effect of the parasympathetic system may be enhanced.
Drug interaction Gliatilin does not enter into drug interaction with other drugs. The drug enhances the effect of levodopa. It can not be prescribed in combination with medicines containing meclofenoxate.
Storage conditions Store the drug in a dry place at a temperature of up to 25 degrees. Storage temperature should not exceed 30 degrees.
Shelf life Ampoules are valid for 5 years, capsules are only 3 years old. The medicine is suitable for 3 years.
Overdose With parenteral administration in large doses, gliatilin can cause nausea, abdominal pain, and impaired consciousness. When taken orally, it can provoke nausea. The drug has low toxicity, so it does not cause an overdose.
Impact on the ability to drive vehicles Drivers can be treated with the drug without any restrictions. During therapy, care must be taken when driving.

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