Gliformin and Metformin, drug choice

Metformin and glyformin are equally effective. They are well tolerated by the body and have identical contraindications. Therefore, any of these agents can be used to treat diabetes. Diabetics with slightly elevated sugar are advised to use Metformin. It is available in tablets with a lower dosage of the active substance. In terms of cost of treatment, it is more profitable to buy Metformin.

The question of what to take, Metformin or Gliformin, is better to ask your doctor. But, as a rule, doctors call these drugs full analogs and see no reason to give preference to any one drug.

In diabetes of the second form, tablet hypoglycemic agents are usually prescribed. These include Gliformin and Metformin. These medicines have many similarities and differences. Therefore, you need to know their description so that it is easier to choose the right drug.


This is a hypoglycemic agent. Its companies are Akrikhin and Farmakor. Available in film-coated tablets. The therapeutic effect is achieved due to the presence of metformin hydrochloride. This substance may be present in amounts of 0.85 and 1 g. Of the additional elements, the center part contains povidone, potato starch and stearic acid. The shell is made of talc, macrogol and hypromellose.


The mechanism of action is based on the inhibition of metformin gluconeogenesis in the liver, a decrease in the absorption of glucose into the blood from the intestine. Doctors prescribe such a medication for diabetes of the second form, when diet therapy does not bring the desired results. Especially often, the drug is used for obese diabetics. The tool can be combined with other hypoglycemic drugs.

The medication should not be taken in such cases:

  • The condition of a diabetic ancestor or coma.
  • Impaired renal function.
  • Hypoxia
  • Severe infectious pathologies.
  • Fever.
  • Pregnancy.
  • Allergy to the composition.
  • Lactation.
  • Alcohol intoxication.
  • X-ray examination, which is planned or was conducted less than two days ago.
The tablets are washed down with water. At the beginning of therapy, administration of 0.5 grams of metformin per day is indicated . After a couple of weeks, the dose is gradually increased. Maximum per day is allowed to use 3 grams of active substance. Older persons are not recommended to exceed a daily dose of 1 g of metformin.

Against the background of treatment, such adverse reactions are possible:

  • Lactic acidosis.
  • Vomiting
  • Epigastric pain.
  • Diarrhea.
  • Hypoglycemia.
  • Allergic rash and itching of the skin.
  • Megaloblastic anemia.
  • Vitamin B12 deficiency.

Packaging tablets in pharmacies in Russia costs about 110 rubles.


This is a hypoglycemic drug. It is produced by pharmaceutical organizations Ozone, Rafarma, Biochemist. It is produced in tablet form. The main substance that has a hypoglycemic effect on the body is metformin hydrochloride. In tablets, it can be present in doses of 0.5 and 0.85 g. Additionally, the center part contains talc, magnesium stearate and corn starch. The shell consists of titanium dioxide, talc, methacrylic acid.


The drug inhibits the process of gluconeogenesis in the liver, increases the sensitivity of tissues to insulin. It is used in the treatment of diabetes mellitus of the second form, especially if a person has a tendency to ketoacidosis. Suitable for use in combination with insulin.

The remedy is prohibited in such conditions:

  • An ancestor or coma.
  • Renal and hepatic impairment.
  • Respiratory or heart failure.
  • Fever.
  • Severe infectious lesions.
  • Lactic acidosis.
  • Intolerance to the composition.
  • Pregnancy.
  • X-ray examination.
  • Chronic alcoholism
  • Breast-feeding.

The tablets are swallowed whole with a liquid. At first, it is recommended to drink 1-2 tablets per day. After 15 days, it is allowed to gradually increase the dosage. Maximum 3 g of metformin can be used per day. Elderly people need a dose adjustment.

Against the background of treatment, such side effects sometimes occur:

  1. Hypoglycemia.
  2. Lactic acidosis.
  3. Megaloblastic anemia.
  4. Flatulence.
  5. Upset stool.
  6. Nausea.
  7. Skin rash and itching.

A pack of tablets costs about 80 rubles.

Comparison: Common Features

Considered hypoglycemic drugs have such similar features:

  • Contain identical active ingredient.
  • Available in tablets with different dosages. They have a film coating.
  • They have a similar reception regimen.
  • Used to treat the second form of diabetes.
  • They have the same side effects and contraindications.
  • They come in one price category.
  • Well tolerated by the body.
  • Have positive reviews from patients.
Comparisons: Differences

The difference between the drugs in question is insignificant. It is as follows:

  1. Release firms. Produced by different countries and pharmacological companies.
  2. The composition of auxiliary components.
  3. Dosage. Metformin is available in a lower dosage.
  4. Cost. Metformin is a little cheaper.

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