25.10.2020

Magnesium lactate and citrate, drug choice

People with vivid symptoms of magnesium deficiency are advised to use citrate-based drugs. They are well absorbed, which means that improvement will come much faster. They are also recommended for patients suffering from constipation in the form of a laxative.

For people with gastrointestinal problems, it is recommended to use preparations with magnesium lactate. It is absorbed more slowly, therefore, it is much safer for the gastric mucosa. Also, based on magnesium lactate, it is recommended to use drugs for pregnant women, if necessary. When taken in the early stages, the chance of normal development of the fetus increases. With a lack of necessary components, including magnesium, the condition of both a pregnant mother and an unborn baby can worsen.

Thus, with a lack of magnesium in the body, it is necessary to replenish it. If this cannot be done with food, then various drugs come to the rescue. What kind of drug to take, the doctor prescribes individually to each patient. Magnesium lactate and magnesium citrate generally perform a single function, but have some differences. Such nuances must be taken into account when using drugs so as not to harm the body.

Magnesium is an important element by which the human body can function normally. It is located in all cells of the body and contributes to the proper generation and distribution of energy. Almost all metabolic processes are carried out due to this element. With its shortage, pharmaceutical companies offer drugs containing magnesium lactate or citrate. To understand the similarities and differences, you need to analyze these two substances in detail.

Magnesium Lactate

This is a synthetic mineral supplement . It is used for the lack of an element in the body (hypomagnesemia), as well as for metabolic disorders. Deficiency is manifested by malaise, rapid fatigue, arrhythmia and seizures.

Magnesium Lactate

Absolute contraindications to the use of drugs with magnesium lactate are:

  • Hypersensitivity to the components that make up the composition.
  • Severe renal failure.
  • Hypermagnesemia (high magnesium in the body).

Relative contraindications are:

  1. Renal failure.
  2. Pregnancy and lactation.

During pregnancy, it is not recommended to use drugs containing this substance. If necessary, admission is carried out only as directed by a doctor . Magnesium penetrates well into breast milk, so breast-feeding should be stopped for treatment.

The daily dose and duration of administration is prescribed by the doctor individually for each patient.

With improper use or contraindications, there is a risk of side effects. Common manifestations are: an allergic reaction (including skin rashes), as well as disorders in the gastrointestinal tract (flatulence, constipation, diarrhea, and others).

Medicines containing calcium salts or phosphates significantly impair the absorption of magnesium ions in the gastrointestinal tract. When taking antibiotics of the tetracycline group and magnesium lactate, it is necessary to maintain an interval of 2-3 hours , since the drugs mutually affect the absorption of each other. Cyclosporin and cisplatin significantly accelerate the excretion of magnesium from the human body.

An overdose with normal kidney function is not dangerous to humans. However, if there is a malfunction in the kidneys, then poisoning may develop. The clinical picture in this case depends on the amount of the drug in the body. The following symptoms are usually observed:

  • Oppression of the central nervous system.
  • Lowering blood pressure.
  • Arrhythmia.
  • Nausea, vomiting.
  • Decreased reflexes.
  • Paralysis.
  • Coma.

It is part of the preparations: Magnistad, Magnelis B6, Magne B6.

Millet to treat kidney

Magnesium citrate

The substance is a magnesium salt of citric acid . Serves as a good source for obtaining this element. In laboratory conditions, it is possible to get it not only from citric acid, but also from the citrus peel.

Magnesium citrate

It is also prescribed for a lack of magnesium in the human body. Most often, people who perform excessive physical exertion, are often subjected to stress, and also abuse alcoholic beverages and laxatives.

Indications for use are:

  • Constipation
  • Arrhythmia.
  • Angina pectoris.
  • Stress and depression.
  • Headache.
  • Osteoporosis.
  • Arthritis.
  • Diabetes.
  • Hypertonic disease.

Contraindication is individual intolerance or hypersensitivity to the components of the drug.

If you have kidney failure, a diet with magnesium restriction, or prolonged abdominal pain, you need to consult a doctor.

People with peptic ulcer or gastritis are recommended to take medications only after eating. In this case, they will not cause irritation of the gastric mucosa.

Included in the composition: Magne B6 Forte, Magnesol, Magvit.

Similarities and differences

The main similarity of these two substances is their composition . In both cases, drugs are prescribed by a specialist to replenish magnesium in the body. Both substances also have a sedative effect.

The main difference between substances is their bioavailability . They are assimilated differently in the body. Also, citrate-based preparations can be used to cleanse the intestines, including before surgery.

Supplemented tablets

Citrate and lactate have different solubilities . This affects the absorption of substances in the body. When conducting research, it was found that chloride, oxide and sulfate (inorganic compounds) have low bioavailability (about 5%). In organic compounds, this figure is much higher. Citrate (36-38%) has the best bioavailability. Therefore, it is best absorbed in the body.

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