16.04.2024

Warfarin and Cardiomagnyl, drug choice

Despite the more affordable price and the ability to prescribe it for free, not all patients choose warfarin. Firstly, it is very difficult to choose the right dosage – you need to monitor the blood condition for several months, taking an analysis almost every day. Secondly, bleeding often begins, especially from the gums. External bleeding can begin even with minimal mechanical damage.

Cardiomagnyl, although it does not harm the mucous membrane of the stomach and duodenum, is still not recommended for use by persons with high acidity due to the possibility of gastric bleeding. Despite this, cardiomagnyl is often preferred to conventional aspirin to reduce the negative effects on the stomach. Since magnesium hydroxide, which is part of cardiomagnyl, belongs to the group of antacids, it is able to reduce the increased acidity of the stomach and reduce the risk of gastric bleeding.

Men after forty-five and women after forty years are strongly encouraged to take continuous and long-term use of aspirin drugs. Only if this condition is met can a significant reduction in the risk of heart attack, stroke, and thromboembolism be achieved. But we must firmly remember that when reaching 80 years, the intake of such drugs must be urgently stopped due to age-related fragility of blood vessels.

To answer the question of which drug is better – warfarin or cardiomagnyl, the pharmacological characteristics of the drugs, their properties and effects on the body should be studied in more detail. At first glance, it may seem that the drugs are interchangeable due to their properties of thinning the blood. However, this is not entirely true.

Warfarin: general information

Warfarin is an antagonist of vitamin K, an antithrombotic agent from the group of indirect anticoagulants. It helps block vitamin K-dependent blood coagulation factors, reduce their concentration in plasma and slow down the rate of blood coagulation. Warfarin is able to reduce the risk of blood clots and is used to prevent blood clots and blockage of blood vessels. The main active ingredient in the drug is warfarin sodium clathrate. Of the additional components, magnesium stearate, calcium hydrogen phosphate, lactose, corn starch, povidone 30, and dye are present.

Warfarin

Warfarin is recommended for use in the following cases:

  • For the prevention of blood clots after myocardial infarction.
  • For the treatment of venous thrombosis in acute and recurrent form.
  • For the prevention of thromboembolic complications after damage to the heart valves, atrial fibrillation and prosthetic heart valves.
  • For the prevention of postoperative thrombosis.
  • For repeated prevention of myocardial infarction.
  • With blockage of the pulmonary artery.

The use of warfarin is contraindicated in the following cases:

  • With pathological changes in the blood.
  • In severe kidney or liver disease.
  • With spinal puncture.
  • With surgical interventions.
  • When psychosis occurs.
  • During pregnancy.
  • After ophthalmic surgery.
  • In acute DIC.
  • If there are prerequisites for bleeding with peptic ulcer.
  • With essential pericarditis and bacterial endocarditis.
  • With malignant arterial hypertension.
  • In severe arterial hypertension.
  • With aneurysms.
  • In diseases with a high risk of bleeding.
  • With excessive alcohol consumption.
  • After cranial operations.

Side effects can occur from various body systems. In case of an overdose, increased bleeding is noted. The use of the drug is contraindicated for pregnant women and persons under 18 years of age. During breastfeeding, the drug can be used.

Cardiomagnyl: general information

This is an anti-aggregation agent used to prevent platelets from sticking together. In this case, blood clots do not form in the blood vessels, and blood is able to circulate freely. Acetylsalicylic acid, or aspirin, and magnesium hydroxide can be distinguished from the active components of cardiomagnyl. The main place is aspirin. It is thanks to him that the formation of blood clots slows down.

Cardiomagnyl

Cardiomagnyl is recommended for use in the following cases:

  • In the primary prevention of acute heart failure and blood clots.
  • In the prevention of repeated cases of blood clots and myocardial infarction.
  • In the prevention of thromboembolism after vascular surgery (coronary angioplasty, coronary artery bypass grafting, etc.).
  • With angina pectoris.
  • With high blood pressure.
  • With high blood cholesterol.
  • With a deterioration in brain function.
  • With migraines.
  • In the post-infarction period for the prevention of relapse.
  • With diabetes, hypertension, functional heart failure, advanced age.

It must be remembered that acetylsalicylic acid – the main active ingredient of cardiomagnyl – can have an aggressive effect on some organs and systems of the body. Cardiomagnyl is not recommended for use if there is an allergy to aspirin, diseases of the gastrointestinal tract, delayed blood clotting and a tendency to bleeding. It is not advisable to take the drug for pregnant and lactating women, children are also better off avoiding it.

What do warfarin and cardiomagnyl have in common

Warfarin is the # 1 drug in the world for the prevention of blood clots. Aspirin also has a significant effect and reduces the risk of thromboembolism by 22%. Warfarin, despite its positive qualities, increases the risk of bleeding much more than aspirin. In case of increased risk of bleeding, it is better to choose aspirin or cardiomagnyl as its improved form.

Cardiomagnyl protects the gastrointestinal tract thanks to magnesium hydroxide. It has a cytoprotective, enveloping effect, reduces the activity of gastric juice by protein breakdown and absorbs pepsin. Both products are available in tablet form.

The difference between warfarin and cardiomagnyl

The choice between warfarin and cardiomagnyl is best done only after consulting with your doctor. You should buy any drug, focusing on a specific disease that already exists in a person. Cardiomagnyl may be offered to patients suffering from coronary heart disease or hypertension.

Warfarin is prescribed to patients if there is atrial fibrillation, heart disease or an increased risk of blood clots.

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