Picamilon or Phenibut, which is more effective

Which drug is better is hard to say. It all depends on the specific pathology, the characteristics of the patient’s body.

“Picamilon” is preferred if a person has a disease that is of the organic nature of occurrence (head injury, strokes, etc.).

It should also be chosen to improve mindfulness and memory.

Phenibut is more appropriate to take when the brain structure is preserved, that is, there is no organic damage, and there are only functional disorders (fear, anxiety, insomnia caused by stress, etc.).

With pathological increased excitability in a child, Phenibut is also better.

In each case, the treatment should be prescribed by a specialist – psychiatrist or neurologist.

In some pathologies, it is possible to prescribe both drugs to enhance the effect of each other, and in others, on the contrary, their combination is unacceptable.

So, to determine which of the drugs to prescribe, and which will be more effective for a particular patient, the attending physician should.

Today, a state such as stress has firmly entered the life of a modern person . This phenomenon is by no means harmless, as it might seem at first glance.

Stressful situations gradually undermine and deplete the nervous system.

A person becomes irritable, forgetful, experiences constant fatigue. There are problems with cognitive functions, sleep disturbance.

In the future, all this can develop into serious nervous or mental disorders.

In such situations, nootropic drugs come to the rescue – tools that can protect the nervous system from the effects of negative factors and improve brain function.

These include medicines such as Picamilon and Phenibut.

“Picamilon”: characteristics of the drug

“Picamilon” is a nootropic drug with a pronounced effect of expansion of the vessels of the brain.


It has antioxidant, psychostimulating, antiplatelet properties. He also has a mild tranquilizing effect.

The drug (PM) helps to improve brain function, increase the resistance of cells to destruction by free radicals.

Due to the antiplatelet effect of drugs, platelet adhesion is suppressed, and blood circulation in the cerebral vessels increases. Tissue metabolism is normalized.

The antioxidant effect of the drug helps to stabilize brain functional activity. This helps improve cognitive function.

The main active ingredient in the composition of the drug is N – nicotinoyl-gamma-aminobutyric acid, which stimulates the metabolic processes in brain cells.

In pharmacies, drugs come in two forms: tablets and a solution for intravenous and intravenous administration.

“Picamilon” is the first nootropic drug synthesized in the USSR in 1970. It is currently produced in Russia at the pharmaceutical standard Pharmstandard.

Indications and contraindications

Appointed in the following conditions:

  • Age Depression
  • ONMK.
  • Stroke (rehabilitation period).
  • Alcohol intoxication.
  • Emotional disturbances (fears, anxiety).
  • VSD.
  • Prevention of migraine attacks.
  • TBI.
  • Asthenic conditions.
  • Depression in the elderly.
  • Neuroinfection.
  • Senile psychosis.
  • Decreased physical and mental performance.
  • State of unjustified anxiety and fear.

In addition, the medicine has shown good efficacy in the treatment of various urination disorders in both adult patients and children after 3 years of age.

The drug does not have a immediate therapeutic effect. It is intended for course treatment. Results will be noticeable after 2-3 weeks of regular use. The full course of treatment is 1.5-3 months.

Contraindicated during pregnancy, lactation, chronic renal failure, childhood less than 3 years., Allergies to components.

Medication rarely shows side effects, its tolerance by patients is usually good. In some cases, nausea, redness of the face (“hot flashes”), headache, skin itching, hypotension may occur.

“Phenibut”: characteristics of the drug

Phenibut is a nootropic and anxiolytic drug with pronounced sedative effect.


The nootropic effect of the drug is manifested in its effect on the integrative function of the human brain. Phenibut enhances the resistance of brain tissue to a variety of harmful factors, such as hypoxia or increased mental stress.

In addition, the nootropic qualities of drugs can normalize brain functions, improve central nervous system circulation, and ensure an efficient metabolic process in brain cells.

By stabilizing blood circulation in the cerebral vessels, the drug increases the volumetric and linear blood flow. Due to this, spontaneous platelet aggregation is reduced, which reduces the risk of blood clots in patients suffering from circulatory disorders.

As an anxiolytic (tranquilizer), the pharmaceutical product reduces the excitability of the limbic structures of the brain, which are responsible for the emotional state, eliminates excessive irritability.

The main active component of the medication is aminophenylbutyric acid hydrochloride, which acts as an inhibitor of the central nervous system mediators in the body.

This pharmaceutical product is available only in tablet form.

Manufacturing countries are Latvia, Russia, and the Republic of Belarus.

Indications and contraindications

It is prescribed for pathological conditions such as:

  • Dizziness due to vestibular dysfunction.
  • Asthenia.
  • Unmotivated fear.
  • An increased sense of anxiety and anxiety.
  • Insomnia.
  • Meniere’s disease.
  • Nightmares.
  • Alcohol withdrawal.
  • Disorders of attention and memory.
  • Emotional lability.
  • Psychopathy.
  • Nervous tics and stuttering in children.
  • Children’s nocturnal enuresis.

It is often prescribed to relieve stress before certain invasive diagnostic procedures or before surgical interventions.

The medicine is usually prescribed in courses lasting 1-1.5 months. If necessary, the doctor can prescribe a second course of treatment, but only on the condition that after the first course at least 3 weeks have passed.

The therapeutic effect becomes noticeable in the first week of treatment.

Do not take medication for people with ulcers or erosion of the gastrointestinal tract, acute kidney failure, individual intolerance to the components, women in position and during lactation, as well as children under 8 years of age.

Despite its low toxicity, drugs can cause side effects. Patients may experience a burning sensation in the stomach, pressure drops, headache, nausea.

Drug similarities
  • Presented drugs are included in one pharmacological group – nootropics.
  • They have the ability to improve blood circulation in the brain, prevent vascular thrombosis.
  • They have a positive effect on mnestic functions, improve intellectual capabilities.
  • Protect brain tissue cells from the effects of internal and external negative factors.
  • The medications in question intersect in a number of prescribing cases (depression, fears, asthenia, etc.)
  • They have a high safety profile and low toxicity, whereby they can be prescribed for children.
  • They have almost identical contraindications and side effects.
  • The cost of drugs is approximately in the same price range. “Phenibut” costs in pharmacies from 78 to 150 rubles, “Picamilon” – from 90 to 113 rubles. in tablets and 145 rubles. in ampoules.
What is the difference

Despite numerous similarities, the drugs have a number of differences:

  1. The main distinguishing feature is a different chemical composition. Despite the fact that the basis of both medicines is “aminobutyric acid”, in “Phenibut” it is present in conjunction with a group of phenyls.
  2. “Picamilon” also contains nicotinic acid instead of phenyl , and due to this it has a pronounced vasodilating effect.
  3. “Picamilon” primarily has a nootropic effect. The second pharmaceutical means more clearly manifests tranquilizing properties, and nootropic are moderate.
  4. Long-term treatment with Phenibut can in some cases cause drug dependence. Therefore, it is sold strictly by prescription. The second drug is not addictive.
  5. The therapeutic effect of Phenibut is faster than that of the second drug.
  6. “Picamilon” dilates the vessels of the brain, which can lead to a fall in A / D. Another pharmaceutical does not have such properties.
  7. The form of release of medicines is also not the same. “Picamilon” is sold in tablet and ampoule forms, the second drug – only in tablets.

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