Chloropyramine is made in Russia, and Suprastin in Hungary. This is reflected in the price: the first one can be purchased for 62-165 rubles, and the second – for 125-260 rubles. According to doctors, Suprastin is considered more popular. According to patients, the one and the other acts similarly.
One and the other is shown to all age groups, starting after the first month of life. There are some warnings:
- Elderly and malnourished may experience dizziness and drowsiness.
- Patients with liver, kidney dysfunction need a dosage adjustment.
- Patients with reflux esophagitis should not take the drug at night, as it enhances the symptoms.
- It is necessary to exclude alcohol during treatment with drugs.
In severe forms of allergic reactions, anaphylactic shocks, it is better to administer the drugs intravenously, and then switch to intramuscular injections or tablets. Which form and which remedy to choose can be recommended by the attending physician. It will take into account the condition, cause, age and weight of the patient. Patients with a chronic form of the disease should always have injections at hand, in case of emergency.
An allergy that manifests itself in a chronic form is caused by a reaction of the immune system to the influence of various substances from outside. Although it does not lead to serious diseases, it causes discomfort and discomfort in the form of a runny nose, sneezing, tears, itching of the face and throat.
Sometimes they are complicated by asthma attacks, abdominal pain, anaphylactic shock. In this case, antihistamines such as Chloropyramine or Suprastin should be at hand. If you choose between them, then which one to give preference?
Antiallergic agent, available in tablet form and as a solution for injection. It is a derivative of ethylenediamine. The name is determined by the main component – chloropyramine hydrochloride.
Its main actions on the body:
- Cholinolytic (moderate).
- Spasmodic (moderate).
Absorption of tablets is carried out in the digestive tract. The effect occurs within 2 hours. It persists for 4-6 hours. Evenly distributed across all life systems. Metabolism occurs in the liver. The role of excretion is given to the kidneys and intestines.
According to the instructions, tablets are taken with food. Injections are in the muscle or vein.
|Tablets||From 1 month to 1 year – 6.25 mg;
from 1 year to 6 years – 8.5 mg;
from 6 years to 14 years – 12.5 mg 2-3r / d
|25-50mg (1-2 tablets) 3-4r / d|
|Injections||From 1 month to 1 year – 5 mg (0.25 ml);
from 1 year to 6 years – 10 mg (0.5 ml);
from 6 years to 14 years – 10-20 mg (0.5-1 ml);
maximum – 2 mg / kg
|20-40 mg (1-2 ml)|
The drug provokes side effects from the gastrointestinal tract:
- Dry oral mucosa.
- Upset stool.
- Gastralgia (rare).
Patients may feel weak, lethargic, drowsy. Sometimes: dizziness, impaired coordination of movement, lethargy.
When using chloropyramine, the recommended dosage must be observed, otherwise symptoms of an overdose in children may appear:
- Convulsive, anxious conditions.
- Excessive agitation.
- Pupil immobility.
- Redness of the face.
All these symptoms can develop into vascular collapse, leading to a coma.
Adults can also experience the effects of an overdose, including depression.
An antiallergic agent is a blocker of H-1 histamine receptors. It is produced in the form of tablets and injection. The main active ingredient is chloropyramine hydrochloride. Due to this component, the drug plays the role of:
- M-anticholinergic blocker.
- Antiemetic drugs.
The absorption of the substance is carried out at the level of the gastrointestinal tract. After 15-30 minutes, a therapeutic effect occurs. Saved for 6 hours. It is perfectly distributed to all organs. Metabolism occurs in the liver. Excretion is carried out by the urinary system. The child’s body copes with this process faster than the adult.
Tablets are shown during meals. The dosage is similar to the dosage of chloropyramine.
According to the manufacturer’s instructions, Suprastin causes adverse reactions in rare cases. This usually happens temporarily. After discontinuation of the drug, the symptoms disappear.
In adults and children, cases of overdose have been recorded, similar to those treated with chloropyramine.
In fact, this is one drug, only a different name. We can say that chloropyramine is an analogue of Suprastin. Both are first generation antihistamines. They have one composition, are produced in one form. They exhibit the same properties, therefore, the indications are similar:
|Allergic conjunctivitis (inflammation of the eye membrane)||Rhinitis, conjunctivitis allergic year-round, seasonal|
|Rhinitis (inflammation of the nasal mucosa) is vasomotor||Hives|
|Hay Fever||Quincke’s Edema (angioedema)|
|Urticaria (nettle fever, rash)||Contact dermatitis, atopic|
|Angioedema edema||Itchy skin|
|Whey Disease||Eczema is chronic, acute|
|Drug rash||Allergy drug, food, insect bites|
|Atopic dermatitis, contact, eczema, toxicoderma|
They have a number of contraindications:
|Hypersensitivity to Ethylenediamine Derivatives||Bronchial asthma acute stage|
|Angle-closure glaucoma||Pregnant, lactating|
|Adenoma of the pancreas (urodynamics)||Newborns|
|Pregnant, lactating||Hypersensitivity to the components of the drug|
|Breasts up to a month||Angle-closure glaucoma|
|Urinary retention, functional impairment of the kidneys / liver|
Medicines enhance the effect of sleeping pills, antidepressants, tranquilizers, painkillers.