29.03.2024

Amelotex and Meloxicam, the choice of drug

Amelotex and Meloxicam are completely interchangeable, the differences between them are insignificant, the only thing if a person is prone to allergies, it must be borne in mind that medicines can have a different composition of additional components.

In the acute period, injections are usually prescribed first, which are given for 3 to 6 days, and then they switch to taking the tablets inside.

If the patient has difficulty swallowing or vomiting, then rectal suppositories or gel are recommended.

An active dosage form of Amelotex is suitable for athletes and people leading an active lifestyle. The gel is effective after training, which can cause injury to the musculoskeletal system.

Also, the external form is recommended for patients who have pathologies of internal organs, such as gastric ulcer, impaired liver and kidney function.

The attending physician should choose the treatment regimen and dosage form depending on the diagnosis, the severity of the pathological process. Self-medication with non-steroidal anti-inflammatory drugs is unacceptable, as this can cause a deterioration in the patient’s well-being.

In the treatment of pathologies of the musculoskeletal system, non-steroidal anti-inflammatory drugs are prescribed. This group of medicines includes Amelotex and Meloxicam.

Amelotex

Amelotex is a domestic drug that contains meloxicam as an active component . A medication is available in several dosage forms:

  1. Oral tablets and rectal suppositories of 7.5 and 15 mg.
  2. Injections for intramuscular administration.
  3. 1% gel for external use.

Amelotex

By the chemical nature, meloxicam belongs to the class of oxycam. It stops the inflammatory process, has a painkiller and antipyretic effect. Meloxicam suppresses the activity of COX enzymes involved in the formation of prostaglandins, which support inflammation in the body. It has an advantage on COX-2 and to a lesser extent COX-1, therefore it rarely causes undesirable reactions from the gastrointestinal tract.

It does not affect the formation of proteoglycan by chondrocytes and does not prevent the development of spontaneous arthrosis.

After oral administration or administration of the drug into the anus, absorption from the digestive tract is 89%. The content of the active ingredient in synovia is 50% of the level of the drug in the blood. Passing through the liver, meloxicam is metabolized. The drug is equally excreted through the intestines and kidneys. The half-life of the drug reaches 20 hours.

Meloxicam

Meloxicam is produced by several domestic and import companies. Therefore, the composition of the indifferent substances of the drug can differ significantly from each other.

Meloxicam

On sale Meloxicam is in the following dosage forms:

  1. Injection solution for the introduction of muscle.
  2. Suppositories inserted into the anus.
  3. Tablets for oral administration.

The last two dosage forms are in 2 dosages of 7.5 mg and 15 mg.

The mechanism of action, pharmacodynamics and pharmacokinetics of Amelotex and Meloxicam are the same.

What is common between drugs

Both drugs available in tablets, suppositories, injection solution are used to treat pathologies of the locomotor system:

  • Osteoarthrosis.
  • Ankylosing spondylitis.
  • Rheumatoid polyarthritis.

Amelotex and Meloxicam do not affect the progression of the pathology, they only weaken the symptoms of the disease, such as pain and inflammation.

Both medicines in these release forms are contraindicated if observed:

  1. Allergy to the composition of the drug and other NSAIDs.
  2. Decompensated heart failure.
  3. The period after coronary artery bypass grafting.
  4. Gastrointestinal ulcer in the acute stage.
  5. Bleeding of various genesis.
  6. Granulomatous and ulcerative colitis.
  7. Severe pathology of the liver and kidneys.
  8. A decrease in potassium in the body.
  9. Age to 15 years.
  10. The period of pregnancy and lactation.

They cause similar adverse reactions:

  • Nausea, vomiting, abdominal pain, stool retention, increased gas formation, loose stools, increased activity of liver enzymes, inflammation of the gastrointestinal mucosa and liver, belching, rupture of the digestive tract.
  • Change in blood picture.
  • Itching, rash, urticaria, photosensitivity.
  • Allergy.
  • Bronchospasm.
  • Dizziness, vertigo, tinnitus, impaired consciousness and orientation, mood swings.
  • Swelling of the extremities, hypertension, hot flashes.
  • Increased creatinine and urea in the blood, the appearance of protein and blood in the urine, acute renal failure.
  • Conjunctival inflammation, vision problems.

With the introduction of the drug into the rectum, false urge to empty the intestine, itching, burning, irritation in the rectum can be observed.

With the introduction of the drug into the muscle, pain and burning sensation at the injection site may appear.

Amelotex and Meloxicam are prescribed in the same dosages.

Comparison and differences

There are the following differences between medicines:

Amelotex Meloxicam
Producing country FarmFirma Soteks CJSC, Russia. It is produced by several companies, for example, PJSC Biositez, OJSC Dalkhimpharm and others.
External dosage form The drug is available in the form of a gel that can be used for osteoarthritis, bruises, dislocations, trauma to the tendon-ligamentous apparatus. It can not be used with intolerance to its composition and other NSAIDs, violation of the integrity of the skin in the area of ​​application, to children.

Gel can cause allergies, photosensitivity, rashes, and redness of the skin.

No.
Price The cost of the drug depends on the form of release, the number of tablets and ampoules in the package, for example, 3 injections cost about 230 rubles. The cost of Meloxicam, depending on the manufacturer, can be either less or more than the price of Amelotex. For example, 3 ampoules made in China cost about 80 rubles, and 5 ampoules manufactured in Israel cost about 600 rubles.

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