28.03.2024

Arthrosan and Meloxicam, the choice of drug

Arthrosan and Meloxicam are completely interchangeable and after consultation with your doctor you can use any of them. For severe pain, it is recommended to use these medicines in injections, which are allowed to be done for no more than 6 days, then if you need to switch to tablet forms.

If the patient cannot take the medicine inside, then rectal suppositories can be purchased. Candles are suitable for people who have vomiting, because of which the medication taken through the mouth does not have time to absorb and have a therapeutic effect.

Both drugs can be bought with a prescription, so self-medication with them is unacceptable. If joint pathologies appear, you should immediately consult a doctor so that he selects a therapy regimen.

Arthrosan and Meloxicam belong to the NSAID group . Both medicines are complete structural analogues and are used to treat degenerative inflammatory diseases of the musculoskeletal system.

Arthrosan

Arthrosan as a main component contains meloxicam. The drug is on sale in injections and tablets of 7.5 mg and 15 mg.

Arthrosan

Meloxicam is a derivative of enolic acid. It relieves pain and inflammation, lowers body heat. Meloxicam blocks the formation of prostaglandins, which support inflammation in the body. The active substance mainly suppresses the second type cyclooxygenase, which is responsible for the development of the pathological process. Meloxicam has less effect on COX-1, so it is less likely to provoke side effects from the gastrointestinal tract.

The drug does not stop the progression of the disease, it only relieves pain and inflammation.

When taken orally, the drug is well adsorbed from the digestive tract. Oral bioavailability is 89%, with intramuscular administration it is 100%. Up to 99% of the dosage binds to plasma proteins.

Meloxicam migrates through internal barriers, the concentration in synovia is 2 times less than in the blood. In the liver, the drug is metabolized. The half-life when taken orally can vary from 15 to 20 hours, with intramuscular administration it is 13-25 hours. The medicine in equal proportions is excreted through the kidneys and intestines.

Meloxicam

Meloxicam is produced by a number of domestic and foreign companies, so the drug may differ in the composition of inactive components. The drug is on sale not only in tablets and ampoules, but in candles inserted into the anus. They come in dosages of 7.5 mg and 15 mg.

Meloxicam

When introduced into the rectum, the bioavailability of meloxicam is 89%.

Both medicines have a similar mechanism of action.

What is common between means

Arthrosan and Meloxicam, regardless of the form of release, are prescribed for pain and inflammation that accompany the following diseases:

  1. Ankylosing spondylitis.
  2. Rheumatoid arthritis.
  3. Osteoarthritis and osteoarthrosis.

Medicines can not be used by pregnant and lactating patients, in addition, they are contraindicated in the presence of the following pathologies:

  • Allergy to the composition of the drug and other non-steroidal anti-inflammatory drugs.
  • Bronchial asthma, urticaria, Quincke’s edema, nasal polyposis, which are caused by acetylsalicylic acid and other NSAIDs.
  • Exacerbation of a gastrointestinal ulcer.
  • Relapse of ulcerative and granulomatous colitis.
  • Marked pathologies of the liver, kidneys and heart.
  • High potassium in the bloodstream.
  • Blood clotting disorder.
  • Bleeding from the digestive tract or brain vessels.
  • Coronary artery bypass grafting.

Treatment with non-steroidal anti-inflammatory drugs can cause many undesirable effects:

  • Decrease in the number of platelets and leukocytes, anemia.
  • Allergy.
  • Changes in mood, impaired consciousness, problems with orientation.
  • Headaches, drowsiness, dizziness, tinnitus, blurred vision, conjunctivitis.
  • Hypertension, hot flashes, palpitations.
  • Bronchospasm.
  • Abdominal pain, diarrhea, constipation, nausea, vomiting, flatulence, belching, bleeding from the digestive tract, inflammation or rupture of the walls of the digestive tract.
  • Impaired liver function, hepatitis.
  • Photosensitivity.
  • Impaired renal function.

Injections of Arthrosan and Meloxicam can cause pain and swelling at the injection site.

If therapeutic dosages are exceeded, drugs can cause poisoning, which is manifested by the following symptoms:

  1. Disorder of consciousness.
  2. Nausea.
  3. Vomiting
  4. Gastralgia.
  5. Internal bleeding.
  6. Impaired liver and kidney function.
  7. Respiratory arrest and heart.

In case of an overdose of drugs based on meloxicam, the antidote is unknown, the stomach is washed out to the victim. If after receipt of large doses of the drug no more than an hour has passed, then you can give enterosorbent, for example, activated carbon. It is known that colestyramine accelerates the elimination of meloxicam from the body. If necessary, the patient is prescribed symptomatic therapy.

Comparison and differences

Arthrosan and Meloxicam have the following differences:

Arthrosan Meloxicam
Manufacturer Pharmstandard, Russia. Vertex, Irbitsky KhFZ and others.
Pediatric Use Injections can only be done to patients over 18 years of age, tablets are allowed from 15 years. All dosage forms are allowed from 15 years.
Indications for use Arthropathy, dorsopathy, including pinching of the sciatic nerve, lower back pain, brachial periarthritis.
Side effects Late ovulation, problems with conception in women. Rectal suppositories can cause a urge to defecate, cause burning and irritation of the rectal mucosa.
Release Forms Pills, injections. Tablets, ampoules, suppositories.
Price The cost of the drug depends on the form of release and the number of ampoules or tablets in the package. The price can vary from 150 to 500 rubles. The price of the medicine may vary significantly depending on the manufacturer. The cost of the drug starts from 40 rubles.

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