27.10.2020

Binavit and Milgamm, the choice of drug

Binavit and Milgamma are completely interchangeable , so after consulting with your doctor you can use any of these tools.

Milgamma compositum tablets are also on sale, which contain pyridoxine and benfotiamine as therapeutic components. They are used for neurological pathologies that are caused by a lack of vitamin B1 and B6. They can not be with hypersensitivity to their composition, children, women in position and breastfeeding.

You can buy them without a prescription, but you should not drink them without consulting a doctor. Moreover, pills can cause allergies, headaches, nausea, neuropathy, acne, sweating, heart palpitations.

Binavit and Milgamma belong to group B vitamins . Both medicines are used for neurological diseases. The vitamins that make up their composition are involved in many biochemical processes in the body, they prevent tissue hypoxia, and improve the function of the cardiovascular system. Both medicines have a similar composition, but differ significantly in price, therefore, for many patients, the question remains which tool to choose.

Binavit

Binavit is available in injections for injection into the muscle, the therapeutic effect of which is explained by vitamins B1, B6, B 12 and lidocaine.

Binavit

In addition to them, the following inactive substances are part of the medicine:

  • Water.
  • E1519.
  • E452.
  • E524.
  • E536.

The injection solution is a clear red liquid with a specific odor.

B vitamins have a positive effect in inflammatory and degenerative pathologies of the nervous and musculoskeletal systems.

Vitamin B1 or thiamine is necessary for the proper metabolism of carbohydrates, it takes part in the Krebs cycle, in the transmission of nerve signals.

Vitamin B6 or pyridoxine is important for the metabolism of proteins, fats and carbohydrates, the normal functioning of the peripheral and central nervous system, blood formation, biosynthesis of catecholamines, transmission of nerve impulses.

Thiamine and pyridoxine enhance the effect of each other and have a positive effect on the heart and blood vessels, nervous system, neuromuscular connection.

Vitamin B12 or cyanocobalamin is involved in the formation of nucleotides and myelin, in the metabolism of folic acid, it is necessary for normal growth and proper development of epithelial cells. Its deficiency leads to anemia.

Lidocaine has an analgesic effect at the injection site, dilates blood vessels, and improves the absorption of vitamins. It blocks the conduct of pain signals along nerve fibers.

After the injection, vitamin B1 is rapidly absorbed into the blood, its maximum concentration is noted after 15 minutes . It is not deposited in the body, therefore it must be supplied with food daily. It is excreted in the urine for 2 days. In the body, vitamin B1 is metabolized.

Vitamin B6 is rapidly absorbed at the injection site, about 80% of the administered dosage binds to proteins. Pyridoxine is metabolized in the liver. It is excreted with urine after 2-5 hours after absorption.

Up to 90% of vitamin B12 binds to proteins, its highest concentration is achieved one hour after the injection. Passing through the liver, vitamin B12 is metabolized. It is excreted in urine and bile, if kidney function is impaired, it can be completely excreted through the intestines.

After introduction into the muscle, the highest concentration of lidocaine is observed after a maximum of 15 minutes . Up to 80% of the dosage is combined with plasma proteins. In the liver, lidocaine is metabolized, excreted in the urine.

All active components of the drug penetrate the BBB and the placenta, excreted in breast milk.

What is CHLS kidney

Milgamma

Milgamma is available in the form of tablets and a clear red injection solution, which has a specific smell.

Milgamma

The drug contains the same therapeutic and auxiliary components as the Binavit medication. They have a similar mechanism of action and pharmacological properties.

The drug must be injected deep into the muscle . Its introduction into the vein is not allowed, if this happened the patient should be under the supervision of physicians, when the patient’s state of health is very difficult, he needs to be hospitalized.

With severe pain, the medication should be administered in 2 ml every day for 5 to 10 days . Further, when the pain subsides or with a mild form of pathology, you need to either reduce the frequency of injections to 2-3 times a week and do them for another 14-21 days or switch to oral intake of B vitamins, for example, drink Milgamma compositum tablets.

What are the similar means

Binavit and Milgamma have common indications for use, they are prescribed in the presence of the following pathologies:

  1. Damage to the nervous system of various origins, including neuralgia, Bell paralysis, neuritis, ganglion affection, plexitis, neuropathy, polyneuropathy.
  2. Muscle cramps that occur at night.
  3. Back pain.
  4. Radiculitis.
  5. Sciatica.
  6. Radicular syndrome, which is caused by degenerative changes in the spinal column.

Both medicines are not used in pediatrics, they can not be pregnant and lactating. They are contraindicated in the presence of the following pathologies:

  • Intolerance to the composition of the injection solution.
  • Acute and uncompensated chronic heart failure.

Against the background of the use of injection solutions, the following adverse reactions may occur:

  1. Allergies, including rashes, anaphylaxis, angioedema, difficulty breathing.
  2. Dizziness, impaired consciousness.
  3. Increased and decreased heart rate, heart rhythm disturbance.
  4. Vomiting
  5. Excessive sweating, acne, pruritus, and urticaria.
  6. Cramps.
  7. Irritation at the injection site.

If therapeutic dosages are exceeded, both medicines can cause intoxication, which is manifested by the following symptoms:

  • Vomiting
  • Heart rate reduction.
  • Arrhythmia.
  • Vertigo.
  • Impaired consciousness.
  • Cramps.

If signs of multivitamin poisoning appear, you need to cancel and go to the hospital, where, if necessary, symptomatic therapy will be prescribed.

Since dizziness may occur due to injections, care must be taken when driving.

Comparison and differences

Binavit and Milgamma have the following differences:

Binavit Milgamma
Producing country Russia. Germany.
Storage conditions Ampoules should be stored at a temperature of no more than 15 degrees. The drug should be kept in the refrigerator at a temperature of 2 to 8 degrees. The injection solution must not be frozen.
Shelf life The drug is suitable for 24 months. The medication is valid for 36 months.
Cost 10 ampoules cost about 240 rubles. The price of 10 ampoules is more than 400 rubles.

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