Isofra or Rinofluimucil, the choice of drug

They are produced in one form – a nasal spray. Apply topically. Do not enter the general bloodstream. They have a decongestant effect.

They are used in the treatment of adults and children. Dosages and terms of application are almost identical. Do not combine with other nasal preparations.

It is very unpleasant to be next to a man with a stuffy nose, who “sniffs” every now and then. It is much more unpleasant to be in the place of this person. But since this inevitably affects everyone, it is necessary to have medications in the home medicine cabinet that help eliminate symptoms and have a therapeutic effect.

For example, Isofra and Rinofluimucil – any of them can be prescribed by a doctor or offer a pharmacist. Having considered each separately, it will become clear what they are and to which one to give preference.

Isofra – a cold medicine

The drug is produced in France. Provided in spray form. In the pharmacological group, it is on a par with antimicrobial, antiparasitic, antibiotics, aminoglycosides.


It is applied only locally. The active substance is framycetin sulfate : 1 ml of spray contains 12.5 mg of the substance.

The liquid is transparent without any special smell. It has few side effects – these are allergic reactions.

Framycetin acts overwhelmingly on various microbes. The therapeutic effect is due to a direct effect on the cells of the mucous membranes of the nasal passages and sinuses.

The bactericidal effect extends to different strains of microorganisms. The latter have practically no resistance to the main substance. Due to this, the upper respiratory tract infection is suppressed.

The drug Isofra does not penetrate the general bloodstream, acting at a local level – inside the nose.

To achieve the desired dosage, it is necessary to make several preliminary sprayings. When administering the medicine, the head should be slightly tilted forward.

The doctor determines the duration of treatment and dosage. Standard dosage for the adult patient category: 1 click in each nasal passage up to 6 times / day.

Children’s category: 1 click in each nasal passage up to 3 times / day.

Standard course – 10 days. If there is no improvement within 5 days, the drug is canceled.

Isofra is not combined with other intranasal drugs. There are no overdose examples.

The spray can be at room temperature up to 25 ° C. It is stored in industrial packaging for up to 3 years.

Rinofluimucil – a means to combat purulent discharge from the nose

The drug is made in Italy. Provided in the form of a nasal spray. In the pharmacological group, it is on a par with decongestants.


It is applied only locally. Active substances: acetylcysteine (1.0 g), tuaminoheptane (0.5 g).

The liquid is not cloudy, it smells like mint. Adverse reactions are extremely rare:

  • Allergy.
  • Heart palpitations.
  • Overexcitation.
  • Increased blood pressure.
  • Tremor in the hands.
  • Dry nasopharyngeal mucosa.
  • Enlarged sebaceous glands.

The drug has a mucolytic property due to acetylcysteine. It liquefies discharge from pus and mucus. In addition, it removes the inflammatory process and is an antioxidant.

Tuaminoheptam has a vasoconstrictive effect on the vessels at the local level. Due to this, swelling, redness of the mucosa is reduced.

While maintaining a certain dosage, none of the active substances penetrates the general bloodstream.

The medicine is injected with a spray into each nasal passage.

Recommended dose for adults: 2 presses up to 4 times / day. For children: 1 press up to 4 times / day. The course is up to 7 days.

Tuaminoheptam can cause an overdose if the recommended doses are not followed. Usually it is expressed in the form of high blood pressure, anxiety, tremor in the hands, tachycardia. In addition, this substance is addictive.

Rinofluimucil is not prescribed in combination with tricyclic antidepressants, MAO inhibitors, and pressure drugs.

What is the difference

First of all, the country of origin. They differ in composition, the main active substances. And so they differ in the spectrum of exposure.

Isofra has a more bactericidal effect, and Rinofluimucil – diluting and decongestant. Rinofluimucil has more side effects than isofra. It can cause overdose and addiction.

In which case and to whom are drugs better suited

Isofra is prescribed along with other medicines to patients with infections and inflammations of the upper respiratory sections.

These include inflammation of the mucous membranes without damage to the sinus walls:

  • Nose (rhinitis).
  • Paranasal sinuses (sinusitis, rhinosinusitis).
  • Nasopharynx (rhinopharyngitis).

The drug is suitable for patients who have inflammatory processes after surgery. The medicine is used for preventive purposes.

Isofra is not suitable for those who have individual intolerance to constituent substances and antibiotics (aminoglycosides). Do not use for children under one year of age, pregnant and lactating.

Rinofluimucil is recommended for patients with a diagnosis of rhinitis:

  1. Acute stage with thick mucus and an admixture of pus.
  2. Subacute stage with mucus.
  3. Chronic stage.
  4. Vasomotor.
  5. Rhinosinusitis (inflammation of the sinuses).

Rinofluimucil definitely will not work if there is a history of:

  • Individual intolerance to one of the components of the drug.
  • Angle-closure glaucoma.
  • Thyroid disease.

The medicine is not used if a person is treated with tricyclic antidepressants, MAO inhibitors. Or if after treatment 2 weeks have not passed.

Caution is prescribed to patients with a diagnosis of:

  • BA (bronchial asthma).
  • Increased blood pressure.
  • Angina pectoris ||| – | V stage.

In the case of extrasystole, repeated with frequent periodicity, therapy is carried out under the supervision of a specialist.

During pregnancy and lactation, treatment with the drug is allowed if the benefit to the mother is higher than the risk to the baby. Any of the drugs can be prescribed by the attending physician, having weighed all the pros and cons.

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