Last reviewed: July 15, 2026. This article is for general information and does not replace advice from your doctor, pharmacist, urologist, gynecologist or another licensed clinician.
Editorial review and sources
Editorial review: osvilt.com Editorial Team
Last reviewed: July 15, 2026
This medical article is based on current public medical sources and follows the osvilt.com Medical Review Policy. It is for general information only and does not replace professional care; see our Medical Disclaimer.
Yarina and Yarina Plus are combined oral contraceptive products built around drospirenone and ethinylestradiol. The main added feature of Plus-type products is folate, usually as levomefolate calcium, intended to support folate status if pregnancy occurs after stopping or after contraceptive failure.
Short answer: Yarina Plus is not a stronger contraceptive simply because it contains folate. Contraceptive reliability depends on correct daily use, missed-pill rules, interactions and whether a combined pill is safe for the patient.
What changed in this update
The article was updated to clarify the folate difference and to add modern safety context for drospirenone-containing combined pills, including blood clot warnings and contraindications.
Yarina and Yarina Plus compared
| Point | Yarina | Yarina Plus |
|---|---|---|
| Hormones | Drospirenone + ethinylestradiol. | Drospirenone + ethinylestradiol, plus folate/levomefolate calcium tablets depending on product. |
| Main purpose | Prevention of pregnancy. | Prevention of pregnancy plus support of folate status. |
| Contraceptive effect | Effective when taken correctly. | Not automatically more effective than Yarina because of folate. |
| Important caution | Combined-pill risks include blood clots, stroke and heart attack in higher-risk patients. | Same hormonal risks; folate does not cancel contraceptive contraindications. |
Who may prefer the Plus version?
A Plus version may be useful when a clinician wants folate support as part of an oral contraceptive plan. This is not the same as prenatal care, and it does not mean pregnancy is intended while taking the pill.
People who may become pregnant should discuss folic acid/folate needs with a clinician, especially if they use medicines or have conditions that affect folate metabolism or neural tube defect risk.
Drospirenone safety points
Drospirenone-containing combined pills are not suitable for everyone. A clinician should review blood pressure, migraine with aura, smoking, age, clot history, kidney/adrenal/liver problems, high potassium risk, postpartum timing and interacting medicines.
Seek urgent care for one-sided leg swelling, chest pain, shortness of breath, sudden severe headache, vision loss, weakness/numbness, severe abdominal pain or coughing blood.
When to ask a clinician first
Get individual medical advice before starting, stopping or switching medicines, contraceptives or supplements, and before treating urinary symptoms at home. Seek urgent care for severe pain, inability to urinate, fever, flank pain, blood in urine, pregnancy-related symptoms, chest pain, shortness of breath, one-sided leg swelling, fainting, or any rapidly worsening condition.
FAQ
Is Yarina Plus better than Yarina?
Not automatically. The main difference is folate support; the hormone contraceptive part is similar.
Can I switch from Yarina to Yarina Plus?
Usually this should be planned with a clinician or pharmacist so the pack timing and contraceptive cover remain correct.
Does Yarina Plus protect against STIs?
No. Condoms are needed for STI protection.
