Cardionate or Mildronate, drug choice

Since the drugs are identical, which and when to take should be prescribed by a doctor.

Some experts during the practice observed some differences in the therapeutic effect. For example, it was noted that Mildronate helps to cope with the consequences of increased physical or mental stress faster, and Cardionate positively affects the work of the heart.

The cost affects the choice of one of the drugs: Cardionate in this regard, of course, is more affordable.

There is no consensus among doctors which drug is better, and often the patient is left with the right to choose.

Some doctors even refuse to prescribe such drugs, since they relate to drugs without evidence of effectiveness. This does not mean that they do not help or have only the “placebo” effect. Only that pharmaceutical companies are not ready to conduct expensive research. However, the private practice of doctors shows that the drugs cope with the stated tasks.

Cardionate and Mildronate are effective drugs, but do not use them without a doctor’s prescription. Often people because of the large workload or training load decide to take metabolic drugs on their own, not knowing the reasons for their true illness. Therefore, it is better to conduct a survey before using such drugs so as not to harm the body.

From time to time, previous performance may decline, fatigue and weakness can be felt, mental and physical strain increases. In this situation, experts recommend taking metabolic drugs. These include Cardionate and Mildronate. They have a similar composition, but still differ. So how does one of them recover and feel better and faster?

Metabolic drugs

Such drugs relate to drugs that stimulate metabolic processes in the body. There is no generally accepted classification, therefore, each individually has a unique mechanism of action and indications for use.

Cardionate and Mildronate are metabolic preparations containing meldonium. Its main function is to increase efficiency and reduce physical and mental stress. Medicines are practically analogues. However, there are some differences between them that will affect the choice of one of them. Which one is better? And which when to take?


Cardionate is a metabolic drug containing meldonium. Relieves symptoms of fatigue, restoring disability, as well as physical and psychological fatigue, reduces the possibility of angina attacks, has a positive effect on the nervous system.


Indications for appointment:

  • Absence or weak ability to work.
  • Physical and mental overwork.
  • Comprehensive treatment and prevention of heart disease.
  • Withdrawal syndrome.
  • Stroke.
  • Violations of the blood supply to the retina and in the brain.
  • Retinopathy
  • The postoperative period.

May cause skin allergic reactions, blood pressure problems, tachycardia, agitation, and dyspepsia. However, such symptoms are rare.

Release Forms:

  1. Capsules of 20, 40 or 100 pieces in a package of size No. 1 (250 mg) and No. 00 (500 mg).
  2. Solution for injection of 5 ampoules.

The medicine is used regardless of food intake, but preferably before evening time.


  • Individual intolerance to the components.
  • Intracranial pressure.
  • Age to 18 years.
  • Pregnancy and lactation.

Before using the medication for renal and hepatic dysfunction, it is worth consulting a specialist.


Mildronate is a metabolic drug. As the main component contains meldonium. Increases energy and accelerates metabolism in chronic diseases, strengthens psychological stability and normalizes physical abilities. It also improves blood circulation in the brain and retina. It has antihypoxic and tonic properties.


Indications for appointment:

  • Dysfunctions of the cardiovascular system (coronary heart disease, angina pectoris, heart failure, myocardial infarction).
  • Circulatory disorders in the retina and brain.
  • Thrombosis.
  • Bronchial asthma.
  • Alcohol withdrawal.
  • Reduced physical and mental abilities.
  • The postoperative period.

It can cause skin allergic reactions, tachycardia, a problem with blood pressure, agitation, less often – weakness, dyspepsia and gastrointestinal problems.

Release Forms:

  1. Capsules of 250 mg and 500 mg of 40 or 60 pieces per pack.
  2. Solution for injection of 5 ampoules.
  3. Syrup 100 ml or 250 ml (with cherry essence).

The introduction or administration of the drug does not depend on food intake, but this should be done in the morning.


  • Individual intolerance to the components.
  • Intracranial pressure.
  • Age to 18 years.
  • Pregnancy and lactation.

With renal and hepatic dysfunctions, you should consult your doctor before using or administering the medicine.

Similarities of funds

In general, Cardionate and Mildronate can be called complete analogues. Therefore, there are a lot of similarities between them:

  • They have the same main component – meldonium.
  • Identical effects on the human body.
  • Identical dosage and methods of use.
  • They have a similar list of side effects.
  • Not recommended for pregnant and lactating women.
  • Contraindicated in childhood.
  • Accumulate in the body.
  • They require additional medical advice from a patient with kidney and liver dysfunction.
  • Both are prescription.
Differences of funds

Cardionate and Mildronate have small differences, so one medicine can easily be replaced by another:

  1. Mildronate appeared on the pharmaceutical market earlier than Cardionate.
  2. The first is produced in Latvia and Russia, and the second – only by Russian companies.
  3. Mildronate causes negative symptoms in case of an overdose, which is not observed when taking Cardionate.
  4. A slight difference in the form of release – Mildronate in addition to capsules and solution is released in the form of a syrup.
  5. Mildronate is more expensive.

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