Prestarium or Prestance, which is more effective

Both drugs help to lower the pressure, but if the doctor prescribed Prestance, then you only need to take it and in no case should you replace it with analogues.

For patients with lactose intolerance, lactase deficiency, glucose-galactose malabsorption, none of these medications is suitable, since they contain lactose.

Prestarium is suitable for those patients who have arterial hypertension, chronic heart failure, coronary heart disease, as well as those who have recently suffered a stroke. The drug will help reduce pressure to normal values ​​and prevent complications, thanks to the vasodilating and restoring effect.

Prestance is intended not only for those who have arterial hypertension, but also for those who have coronary artery disease with stable angina pectoris. The drug, thanks to amlodipine, normalizes the functioning of the heart muscle and eliminates angina pectoris.

To say which medication is better is impossible. Prestance is better because it contains amlodipine, which has an additional effect. But some patients may have intolerance to amlodipine, and only the Prestarium is allowed for them. Therefore, everything is individual.

Despite the fact that these medicines have almost the same composition and similar contraindications, it is contraindicated to take them without a doctor’s prescription. Self-medication can lead to side effects and serious complications, including death.

People with high blood pressure and some diseases of the cardiovascular system need to take special medications to prevent complications. Prestarium and Prestanz are the most effective and commonly used medications to lower blood pressure.


Antihypertensive drug. Helps lower blood pressure, reduces pressure in the pulmonary capillaries. It restores the elasticity of large arteries, reduces hypertrophy of the heart muscle, and moderately reduces the heart rate.


Active substance: perindopril.

Release form: tablets on 2, 4 and 8 mg.

Indications for use:

  • Arterial hypertension.
  • Chronic heart failure.
  • Prevention of the development of cardiovascular complications in patients with coronary artery disease.
  • Prevention of re-stroke.

It can not be used for intolerance to the substances that make up the product, Quincke’s edema (history), during pregnancy (including in preparation for pregnancy) and lactation.

It is made in France. Released by prescription.


Combined antihypertensive drug. Helps reduce blood pressure and dilate blood vessels, restores the elasticity of large arteries.

Active substances: perindopril and amlodipine.

Release form: tablets.


Indications for use:

  • Arterial hypertension.
  • Coronary heart disease, accompanied by stable angina pectoris.

Contraindications for use:

  • Intolerance to the substances that make up the product.
  • Quincke’s edema (history).
  • Low blood pressure (with coronary heart disease).
  • Any kind of shock.
  • Aortic stenosis, obstruction of the ventricular outlet tract.
  • Age less than 18 years.
  • Pregnancy and the period of preparation for pregnancy.
  • The period of breastfeeding.
  • Metabolic disorders: lactose intolerance, lactase deficiency, glucose-galactose malabsorption.

It is made in France. Released by prescription.


The drugs belong to the same pharmacological group and have the same properties:

  1. Lower blood pressure.
  2. Expand blood vessels.
  3. Large arteries are made more elastic.
  4. Normalize the work of the heart muscle and prevent its hypertrophy.

The drugs have the same healing properties due to the fact that they contain the same active substance – perindopril. It is he who provides a decrease in pressure in the arteries and the restoration of their elasticity.

The drugs are available in tablets and have the same indications for use: arterial hypertension, prevention of complications of coronary heart disease. Also, these drugs are taken for some other cardiovascular pathologies in order to prevent complications.

These medicines are absolutely contraindicated for pregnant and lactating women. ACE inhibitors have been proven to negatively affect fetal development in the womb and can cause congenital abnormalities in the kidneys, heart, brain, and other organs. Women planning a pregnancy should cancel their medication and replace it with another one that is safe for pregnant women.

Also, funds are contraindicated for persons under 18 years of age and for those who have ever had Quincke’s edema.

The maximum antihypertensive effect of drugs is achieved 4-6 hours after administration and persists throughout the day. Persistent normalization of pressure occurs after 1 month of regular intake of tablets and persists for a long time. In this case, after the cancellation of any medication, a sharp jump in pressure does not occur.

Both drugs are produced in France (Prestarium is also produced in Russia and Ireland). They are released only by prescription.


The main difference between Prestance and Prestarium is that it contains not only perindopril, but also amlodipine, which has an additional antihypertensive effect and enhances the effect of the drug. It should be borne in mind that Prestarium can be replaced by Prestance, but vice versa – not.

The first medication has more indications for use. It is prescribed not only for hypertension and ischemia, but also for heart failure, and after a stroke.

If we compare the contraindications, then Prestance has a lot more than the first drug. This is due to the fact that Prestanz additionally contains amlodipine.

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