20.04.2021

Cifran or Ciprolet, drug choice

Patients are often interested in which of the drugs to choose. Both drugs are available in the same forms: tablets, infusion solution and eye drops. They also have the same active substance and they belong to the same pharmacological group. They have similar indications and they affect microorganisms almost identically.

The only difference is the fact that in the product line there is Tsifran with additional components (Tsifran OD). It is able to destroy any pathogenic microorganisms. Another difference is that Tsifran is allowed to be taken to children from 12 years old, while Tsiprolet is prohibited until 18 years old. Also the difference is the cost of drugs. Cifran is a cheaper drug compared to its counterpart.

Having studied both drugs, we can conclude that the differences between them are insignificant. They have the same indications and contraindications. However, the patient should not self-medicate, the drug should be prescribed by a doctor. The choice is based on the recommendations of the doctor, as well as the availability of the drug in the nearest pharmacies. Some doctors believe that Ciprolet is more effective than its counterpart. This is due to the fact that the drug is released by an Indian company. It is thoroughly cleaned of mechanical impurities, which reduces the number of side effects.

Thus, both drugs are almost the same. This is not to say which drug is better. Treatment should be prescribed exclusively by a doctor, based on the characteristics of the patient’s disease. Any antibacterial drugs should be taken with caution, and a dosage violation threatens to develop side effects.

The culprits of most inflammatory diseases are pathogenic microorganisms. Pharmacological companies offer a wide range of antibacterial drugs that effectively fight pathogenic microflora. These also include Tsifran and Tsiprolet. Some patients are interested in which of the drugs is more effective. To make a choice, you need to study them in more detail.

Digital

This is an antibacterial drug belonging to the group of fluoroquinolones. The active substance is ciprofloxacin hydrochloride. Available in the form of tablets, eye drops and infusion solution.

Digital

Destroys the cell membrane of bacteria, which allows them to destroy. It has an effect on bacteria, not only in the breeding phase, but also in the resting phase. The drug does not violate the intestinal and vaginal microflora. It acts on gram-positive and gram-negative bacteria that other antibiotics cannot cope with.

Quickly absorbed from the gastrointestinal tract. Bioavailability is 70%. When ingested, it is evenly distributed in the tissues. Cerebrospinal fluid also enters. It is excreted in the urine with bile and feces.

Indications for use are infectious inflammatory diseases whose pathogens are sensitive to ciprofloxacin. These include:

  • Respiratory diseases (pneumonia, bronchitis, lung abscess).
  • Infections of ENT organs (sinusitis, otitis media, tonsillitis).
  • Eye infections.
  • Infections of the gastrointestinal tract (peritonitis, typhoid fever).
  • Genitourinary infections.
  • Soft tissue infections due to injuries and burns.
  • Osteomyelitis, septic arthritis.

In the presence of postoperative infections, intravenous administration is used.

Contraindications are:

  1. Individual intolerance.
  2. Atherosclerosis.
  3. cerebrovascular accident.
  4. Mental illness.
  5. Epilepsy.
  6. Renal and liver failure.
  7. Children under 12 years old and elderly.
  8. Pregnancy and lactation.

The use of the drug should be carried out only under the supervision of a physician.

The dosage is set individually for each patient, based on the characteristics of the disease, the pathogen and the general condition of the body.

For children after 12 years, the dosage is calculated from the scheme of 5-10 mg / kg body weight per day. Usually the dose is divided into two doses. It is recommended to take before meals.

The average dosage is 200 mg per day. The maximum is 400 mg.

The duration of treatment is determined individually, but usually is 5-7 days. After eliminating the symptoms, the medicine is recommended to take another 3 days.

Eye drops are instilled in 1-2 drops every 4 hours.

Tsiprolet

An antimicrobial drug belonging to the group of fluoroquinolones. The active substance is ciprofloxacin hydrochloride. When taken orally, it is rapidly absorbed from the digestive tract. Bioavailability is 50-85%. The maximum concentration is observed in the blood after 1.5 hours. Also, the active substance is distributed throughout the body, getting into all tissues and fluids.

Tsiprolet

The main route of elimination are the kidneys. The elimination half-life is 3-5 hours with normal kidney function. With kidney disease, time increases significantly. About 70% of the substance is excreted in the urine, and the rest with feces.

Indications for use are:

  • Respiratory diseases (bronchitis, pneumonia).
  • Infections of ENT organs (otitis media, sinusitis, sinusitis).
  • Genitourinary infections.
  • Gallbladder Infections.
  • Skin infections (abscess, boil, carbuncle).
  • Musculoskeletal infections.
  • Sepsis.
  • Hydronephrosis.
  • Peritonitis.

It is also used to prevent diseases in people with reduced immunity, together with immunosuppressants.

Contraindications are:

  1. Individual intolerance to the components.
  2. Pregnancy and lactation.
  3. Pseudomembranous colitis.
  4. Liver disease.
  5. Children under 18 years old.

It is prescribed with caution to patients with mental illness, atherosclerosis, and epilepsy.

Dosage is determined individually. The average daily dose is 250 mg, and the maximum is 500 mg. In case of impaired renal function, the dosage is reduced by 2 times.

The dosage for intravenous administration is determined by the attending physician depending on the disease.

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