Ambene (Ambene) – analgesic, anti-inflammatory drug. The tool is a vial of solution. It is injected intramuscularly.
Happens in two-chamber syringes, produced and tablets. The composition of the set of Ambene in syringes: a band-aid and syringe, cloth. The drug is instructions for use.
Manufacturer country of Germany. There are analogues of the drug (drugs which have a similar composition).
To the drug included detailed instructions, which describes the drug. The glucocorticoid dexamethasone and the NSAID phenylbutazone is a anti-inflammatory components.
Included in sostav Phenylbutazone NSAIDs acts as an analgesic substance, an antipyretic. Salicylamide-o-sodium acetate facilitates easy, rapid dissolution.
Cyanocobalamin regenerates cells, synthesizes the nucleic acid, promotes the formation of myelin nerve fiber layer, activation of the lipid metabolism.
This component in the composition of the solution is in large quantity to enhance the analgesic action. Lidocain make the injections completely painless. Active components included in the Ambene enhance the interaction of each other, reducing the dose of dexamethasone.
Since they separated the two solutions (A and B), the activity of this medication lasts a long time (about 36 months).
In the packaging of medicines 2 capsules with different contents.
- 2 ml of solution A.
- To -1 ml.
Solution And ampoule No. 1 contains the following substances: dexamethasone 3,32 mg; special water for injections 1675,92 mg; sodium hydroxide And mg. of 49.08 solution contains: lidocaine hydrochloride 2 mg; water for injections 996,5 mg; cyanocobalamin 2.5 mg.
Drug medicine Ambene appropriate in ankylosing spondylitis, sports injuries, sciatica, neuralgia, degenerative spine diseases, arthritis, and osteoporosis, neuritis.
In some cases, the drug is not introduced
The entrance studying the instructions and reading the reviews about the drug, you can highlight several contraindications of the drug:
- sensitivity to the components;
- diseases of the gastrointestinal tract;
- diseases of the cardiovascular system;
- disorders in the kidney, liver;
- viral infection;
- pregnancy, breast-feeding period;
- glaucoma, myopathy;
- advanced age, children under the age of 14 years;
The drug is instructions, detailed study which reviews the drug, the following side effects:
- allergic reactions;
- from the nervous system;
- of the cardiovascular system;
- on the part of the digestive system.
Allergic reactions: bronchospasm, syndromes such as Lyell, Johnson -Stevens, itchy skin, peeling. Arterial hypotension, aplastic anemia, orthostatic collapse, thrombocytopenia is cardiovascular disease.
Disorders of the digestive system: diarrhea, anorexia, bleeding of the gastrointestinal tract, vomiting. Can manifest a number of unpleasant manifestations of disorders of the nervous system: insomnia, dizziness, mental disorder, headache, restlessness.
If you manifest any of the above symptoms, discontinue the injection and seek medical advice.
Ambene is administered intramuscularly (deeply and slowly). The injections are every day or every other day. Need a break for a few weeks.
And the first solution into the syringe type, the solution In behind him. Pills washed down with water (a small amount). Take the following scheme: day the first 2-3 tablet; day 2, 3, 4, 2 tablets; day 5, 6,7 th 2 tablets 12 hours later; day 7, 8, 9, 10 on tablet.
Interactions with drugs
Simultaneous application of funds Ambene with different anti-inflammatory drugs that contain ethyl alcohol in the composition, produces bleeding from the gastrointestinal tract.
If you enter insulin, medicines with anti-diabetes, possible hypoglycemia or hyperglycemia. If you enter Ambene and indirect effects anticoagulants, dipyridamole, sulfinpirazon, there is a need to correli doses.
The solution raises level of plasma concentrations of sulfonamides, drugs lithium, methotrexate toxicity. During the use of drugs with phenytoin and Ambene may be intoxication. The drug enhances the sedative action of barbiturates.
The purpose of the drug with cardiac glycosides may speed up or slow down the digitalization of patients. The tool reduces the effect of antihypertensives. Also, it may reduce the contraceptive effect of contraceptives.
If any side effects while using drug or no drug at the pharmacy, it can be replaced by analogues. There are analogues: Ambene Parenteral, Humira, arava, Aklast Remicade, Enbrel.
Independently change the drug Ambene counterparts is strictly prohibited requires the prior consultation of the doctor. Also, you need to forget about reviews analogues.
If there is a need to study the functional capacity of the thyroid gland, the study to spend later, 2 weeks after injection in ready-made syringes, to avoid misrepresentation of laboratory performance.
The drug be stored in a dark place. The temperature should not превышать25°C. can be bought only if you have a prescription.