Karipazim or Karipain, which is more effective

When appointing, it is difficult to immediately understand which of the funds is best for the patient.

However, for some facts, one of them can be preferred:

  • Temporary options: 30 sessions with Karipazim or 20 with Karipain.
  • Availability: the cost of the drug is a more expensive analog or original at a lower price.
  • Additional therapy: whether the patient needs it, if necessary – Caripain capsules in this case are suitable.
  • Difficulty of the disease: in more severe cases, doctors give preference to the proven Karipazim, but if it is necessary to restore cartilage, they will choose Karipain Plus.
  • The choice of one of the means can solve the individual intolerance of the components of one of them.

Caripazim and caripain are analogues, so any of them may be suitable for treatment. They are an alternative to surgery. However, to what extent these tools can help in the treatment, the specialist must decide.

With a constant sedentary and abnormal lifestyle, you can have diseases of the musculoskeletal system : hernia and osteochondrosis. In complex cases, surgical intervention may be required. However, in the early stages, medication with Karipazim or Karipain may help. In what cases will one of them be prescribed? And which is better?

Medicines containing proteolytic enzymes appeared on the pharmacological market around the 60s. They have become a humane alternative in the treatment of the musculoskeletal system. The main substance in such medicines is papain. In addition, proteolytic enzymes began to be used in neurosurgery, ophthalmology, gastroenterology, uralogy. They contribute to the destruction of amino acid proteins and dead cells, without affecting normal ones. Thus, they have anti-inflammatory, bactericidal, analgesic effect.

Karipazim and Karipain belong to the group of drugs containing papain – an enzyme of dried papaya milk juice. However, they differ in additional substances, so they can have a different therapeutic effect. How do they differ? What medicine and when to take?


Karipazim is a proteolytic agent of plant origin. The main substance is papain. It is characterized by necrolytic, anti-inflammatory, regenerative action. Eliminates pain and inhibits progressive disruption of the structure of the intervertebral discs. Restores blood circulation between them.


Indications for appointment:

  • Burns.
  • In the complex therapy of diseases of the spine and soft tissues of the back (osteochondrosis, herniated discs, arthritis, arthrosis, discogenic radiculitis, spinal and cerebral arachnoiditis).
  • Keloid scars.

With burns, it accelerates the regeneration process, freeing wounds from suppuration and necrotic tissue. Beneficial effect on the cartilage of the vertebrae and strengthens them. Of the negative effects, an allergic reaction is possible.

Method of release: lyophilisate for the preparation of a solution of 10 ml.

For the treatment of musculoskeletal diseases, the solution is administered using electrophoresis. It can also be used for burns.


  • Individual sensitivity to components.
  • Sequestration of disc herniation.
  • Exacerbation of inflammatory processes.
  • Childhood.
  • Pregnancy and lactation.

The medicine is not used in the form of injections. It is released only by prescription.


Caripain is a fermented herbal preparation. The active substance is papain. It has anti-inflammatory, analgesic, bactericidal and regenerative effects. Helps relieve acute symptoms of pathologies and chronic forms of diseases of the musculoskeletal system.


Indications for appointment:

  • Combined therapy for pathologies of the spine and soft tissues (osteochondrosis, intervertebral hernia, discogenic sciatica, osteoarthritis, arthrosis, arthritis, hernia of the spinal column and discs).
  • Keloid scars, scars.
  • Prevention of articular pathologies or relapses.

The medicine promotes tissue regeneration by normalizing blood circulation between the vertebral discs. Because of the negative effects, an allergic reaction is observed.

Release Forms:

  1. Capsules 60 pieces per pack.
  2. Dry balm for external use (in the form of a prepared solution) in a bottle.
  3. Dry balm Caripain plus (for solution).
  4. Cream 50 ml.
  5. Gel 30 ml.

Dry balm is applicable together with electrophoresis. Cream and gel are applied between treatments with it. Capsules are taken 2 times a day for a month.


  • Individual intolerance to the components.
  • Acute inflammatory processes.
  • Sequestration of disc herniation.
  • Childhood.
  • Pregnancy and lactation.

When using the medicine, physical activity should be excluded. Dry balm can only be obtained by prescription, the rest – without it.

Similarities of funds

In general, Karipazim and Karipain are analogues, therefore, they have many similarities:

  • They have an identical active substance.
  • Used in the treatment of the musculoskeletal system and soft tissues.
  • They have few side effects.
  • They have the same contraindications.
  • Both are effectively used with electrophoresis.
  • Not suitable for children and pregnant women.
  • Do not apply if strong anti-inflammatory processes are observed.
  • Available with a prescription.
Differences of funds

Despite the similarities, there are differences between them that can affect the choice of one of the means:

  1. Karipazim appeared on the pharmacological market earlier, so Karipain is its analogue.
  2. Caripain has a milder composition of substances, so it has less side effects.
  3. Karipazim should be used for approximately 30 sessions with electrophoresis, Karipain – 20, since it acts faster and more efficiently.
  4. Karipain has different forms of release, which allows it to be used more comprehensively, separately from electrophoresis, and capsules can be used without a doctor’s prescription.
  5. Caripain is more expensive.

Sometimes there is information that it is not just an analogue of Karipazim, but is not considered a medicine, but only a dietary supplement. This, of course, is not so. They are produced by different manufacturers, but both have the appropriate certificates for medical purposes.

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