Midokalm or Kalmireks, which is more effective

Medicines Midokalm and Kalmireks are used:

  1. For relaxation of increased tone, spasm of striated muscles with stroke, encephalomyelitis, myelopathy, multiple sclerosis.
  2. When recovering from orthopedic operations and injuries.
  3. To correct disorders in the musculoskeletal system, with spondylarthrosis, arthrosis of the joints, cervical and lumbar syndrome, spondylosis.
  4. With the complex therapy of obliterating diseases of the arteries, with atherosclerosis or thromboangiitis, diabetic angiopathy, diffuse scleroderma.
  5. With a disorder of vascular innervation (acrocyanosis), in the treatment of various types of paralysis. Complex treatment is prescribed.

The action of drugs relaxes striated muscles, reduces pain, enhances peripheral blood flow, and provides a membrane-stabilizing state. Improving motor and sensory functions while relaxing muscles, allow the patient to remain able to work.

Medications are taken by adult patients after eating. The dose will be determined by the doctor, in connection with the individual characteristics of the patient. In the absence of contraindications, the drug is prescribed 1 tablet 3 times a day. Reception begins with a reduced dose of the drug. As necessary, the dosage of the drug may increase.

Intramuscular injections of the drug are made twice a day in one ampoule. With intravenous administration of muscle relaxants, one ampoule is enough 1 time per day. The drug is taken for no more than 10 days. Its effect after administration or administration is observed no earlier than 0.5-1 hours. Studies have shown that the inclusion of centrally acting muscle relaxants in the treatment regimen reduces the patient’s healing process.

Muscle relaxants are used in treatment regimens, including non-steroidal anti-inflammatory drugs, antibacterial drugs, alcohol-containing drugs. Their compatibility with alcohol-containing drugs is proven.

The use of central muscle relaxants in the treatment of certain diseases helps to accelerate the healing process of patients. These drugs reduce the degree of muscular tension, improve local blood circulation, and reduce pain.


The muscle relaxant Midokalm is produced by the manufacturer in the form of white biconvex tablets coated with a film coating, on which, on one side, the amount of active substance – tolperisone is marked by engraving : 50 mg; 150 mg The tablets have a characteristic odor. Excipients, compositions of film membranes perform a form-forming function.


The manufacturer produces Midokalm ampoules with a solution for intramuscular and intravenous administration of the drug. The solution is clear, colorless, with a specific smell. It consists of: tolperisone hydrochloride – 100 mg / ml ; lidocaine – 2.5 mg / ml. Prescription drug for sale. Manufacturer – Hungary.

Packages of tabletted funds are 3 blisters in a cardboard box with attached instructions for use. One blister – 10 tablets. Midokalm for injection is sold in a cardboard box containing a package of 5 ampoules and an enclosed instruction. The shelf life of the drugs is 3 years.


The drug Kalmirex is produced in tablets and ampoules. White tablets, the active substance is tolperisone. Tablet formulations are available with 50 mg and 150 mg of active ingredient. Excipients of tablets do not affect the medicinal properties of muscle relaxant. The drug is sold in cardboard boxes with 3 blisters of 10 tablets.


The release of Kalmirex ampoules is made of 5 pieces per pack. The implementation includes cardboard boxes with 1 or 2 packages of ampoules enclosed, instructions for use. One Kalmyrex ampoule contains 100 mg / ml tolperisone hydrochloride and 2.5 mg / ml lidocaine hydrochloride. A solution with an appropriate odor, clear, colorless.

Released by prescription. The manufacturer of Kalmireks is Russia. Shelf life of the drug is 2 years.

The similarity and difference in the use of muscle relaxants

Medicines Midokalm and Kalmireks are identical in composition and concentration of the active substance – tolperisone. In tablets, this component is 50 mg and 150 mg. Ampoules for injection contain 100 mg / ml of tolperisone hydrochloride. For pain relief by injection, lidocaine hydrochloride 2.5 mg / ml was added to the ampoules.

Excipients used in the composition of preparations for shaping and preservation are different. But this difference does not change the basic properties of drugs when used. The exception is individual patient intolerance to auxiliary components.

Hungarian Midokalm has been used for treatment as a myolaxing, membrane-stabilizing, local anesthetic agent for more than 50 years. For such a long period, the drug passed a natural test, its weaknesses, strengths were revealed. Therefore, comparing with the Russian Kalmireks, the scope of application of Midokalm is expanded by the manufacturer.

It is allowed to use a Hungarian preparation in tablet form for the treatment of children from 3 years old. If absolutely necessary, the doctor may prescribe this medicine for a one-year-old child. Midokalm injections are contraindicated in children. Treatment of pregnant women is allowed in cases where the benefit significantly exceeds the perceived risks. Only a doctor can decide whether to prescribe a muscle relaxant or not.

The dose of medicine for children is calculated as follows:

  1. A child from 1 year to 6 years is prescribed 4-5 mg / kg of body weight.
  2. Children from 7 to 14 years old – 2-3 mg per 1 kg of their weight.

Pills are taken after meals, washed down with a small amount of water.

Russian Kalmireks in the pharmaceutical market recently, so the manufacturer is careful. Instructions for use prohibit the use of the drug for the treatment of women during pregnancy and during lactation, children under 18 years of age.

Indications for use are the same. Side effects of various body systems on drugs are extensive, but are rarely observed. Common contraindications are myasthenia gravis, allergies to any components of the drugs, breast-feeding. Interaction with other medicines is not noted. The difference in the price of muscle relaxants is not significant.

With an overdose of drugs, serious consequences can occur : respiratory arrest, tonic and clonic convulsions. Ataxia, dyspnea are possible. They have no antidote. Supporting treatment for the identified symptoms will help.

The body of each person is individual in itself, in addition there may be concomitant diseases, it is necessary to take into account the severity of the disease that remains to be treated. Only a doctor can analyze the situation, prescribe medication. If symptoms of worsening of the patient’s condition occur, timely medical care will be provided.

Side effects when using muscle relaxants

Reception of Midokalm and Kalmireks at the same time is unacceptable. Take drugs should be under the supervision of a medical specialist. Since side effects are possible or there are contraindications for use.

The doctor will take into account the patient’s condition, the complexity of the disease, compatibility with other drugs used in complex treatment. If the patient has impaired liver or kidney function, treatment with these muscle relaxants should be carried out with caution.

When using Midokalm and Kalmireks side effects are rare, but they should be taken into account, this:

anorexia, anemia, anaphylactic shock, bradycardia, lethargy, vertigo, depression, gastrointestinal discomfort, dizziness, headache, itching, constipation, tinnitus, skin rash, urticaria, lymphadenopathy, muscle weakness, flatulence, blurred vision, and malaise, shortness of breath, polydipsia, sleep disorder, vomiting, angina pectoris, tremors and convulsions, tachycardia, decreased blood pressure.

The manifestation of side effects can be not only during the period of taking medications, but also after a course of treatment. Therefore, it is very important that the patient be treated by a medical specialist until complete recovery. To avoid deterioration when one or more side effects occur.

The choice between Midokalm and Kalmireks is not fundamental, since they are identical in all respects. But Midokalm is time-tested, and Kalmireks still undergo natural tests. If the patient does not have individual intolerance to the components of this drug, then the advantage is on the side of Midokalm.

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