Nitroxoline or 5-NOC, which is more effective

Based on comparative characteristics, we can say that the question of which of the pharmaceutical drugs to choose is not important in this case. These are almost the same drugs. But judging by the reviews of experts, it is better to purchase 5-NOC. It acts on the body more gently than Nitroxoline.

This is due to the best quality of the drug. It undergoes more thorough cleaning and pharmacological control.

Although urologists prefer domestically made tablets to treat very small patients.

Separately, I would like to say about people with diabetes. Neither one nor the other drug is suitable for them. Both contain sugar as an adjuvant. For such patients, the doctor will choose to replace the antimicrobial medication with a similar one in action, but not containing sugar.

In other cases, you can purchase any of the drugs. If it is not possible to buy an expensive pharmaceutical product from a Slovenian manufacturer, you can always replace it with domestic medicine, much lower in cost. The effectiveness and quality of treatment will not be affected.

But, of course, before purchasing any of the drugs, you need to consult a specialist.

Urogenital diseases can occur for a variety of reasons. But still, most of them are of an infectious origin. To destroy the harmful bacterial flora, urologists often prescribe antibacterial drugs to their patients.

The range of drugs created for these purposes is quite wide.

Among them, the most commonly prescribed medications are Nitroxoline and 5-NOC, which are essentially analogues.

Accordingly, the patient questions what means to choose and whether there is a difference between the two. To understand this, consider both drugs in more detail.

“Nitroxoline”: characteristics of the drug

“Nitroxoline” is an antibacterial drug from the group of oxyquinolines. It features a wide range of action.


Actively destroys both gram-positive and gram-negative microorganisms (staphylococci, streptococci, E. coli, Salmonella, diphtheria bacillus, Proteus, etc.)

In addition, the medicine has a proven antibacterial effect against Koch’s bacillus (the causative agent of tuberculosis), fungi of the genus Candida, Trichomonas.

It has a detrimental effect on molds, dermatophytes, as well as on a number of parasitic fungi that cause deep fungal infections.

Such a wide range of effects allows the use of Nitroxoline not only for the treatment of various pathologies of the genitourinary system caused by a bacterial infection, but also for the treatment of any infectious disease (pneumonia, bronchitis) provoked by any of the above microorganisms.

The drug exerts its therapeutic effect by blocking the synthesis of DNA of microbes. Due to blockage, bacteria lose their ability to reproduce. A cell that is unable to reproduce does not live very long, then dies.

The medication has the ability to act selectively (selectively) only on pathogens. It does not have a negative effect on organs, tissues of the human body.

“5-NOC”: characteristics of the drug

“5-NOC” is also an antibacterial drug oxyquinoline group. It is positioned by the manufacturer as an antimicrobial agent with a wide spectrum of action.

It is active against most bacteria that cause inflammatory diseases of the urinary tract (E. coli, Mycoplasma, Streptococcus, Ureaplasma, Staphylococcus).


Destroys gonococci, salmonella, various fungi, including candida and dermatophytes.

Effective against pathogens of diphtheria and tuberculosis.

It is widely used in the treatment of infectious and inflammatory pathologies of the urinary tract and a number of other bacterial infections caused by drug-sensitive microbes.

Selectively affects the synthesis of pathogen DNA, suppressing it. Infected cells die as a result. Further expansion of the infection ceases.

The selective structure of the drug allows it to destroy only pathogenic cells without harming other systems of the human body.

What are the similarities of drugs

Representing structural analogues, the considered tools have similarities in almost all parameters.

Both belong to the group of antibacterial agents. They have the same active ingredient as the main component – nitroxoline.

The amount of basic substance in both medicines is equal – 50 mg per 1 pill.

Available in tablet form only. They have the same therapeutic effect.

The list of indications for use is completely identical. Medications are prescribed for:

  1. Urethritis.
  2. Pyelonephritis.
  3. Cyste.
  4. Prostatitis.
  5. Epididymitis.
  6. Carcinoma and prostate adenoma complicated by infection.

In addition, both drugs can be used to prevent infectious complications after surgery on the genitourinary tract or kidney or during diagnostic procedures (cystoscopy).


  • Pregnancy.
  • Cataract.
  • Severe hepatic or renal failure.
  • Lactation.
  • Hypersensitivity to nitroxoline or auxiliary components.
  • Intolerance to quinolines.

The list of side effects is the same. Patients may experience nausea, polyneuropathy, ataxia, tachycardia, headache, vomiting, skin rashes.

What are the differences

Differences between pharmaceuticals, although insignificant, still exist. “Nitroxoline” is undesirable for people suffering from neuritis (any nerve). In the instruction to “5-NOC” there is no such prohibition. “5-NOC” is not prescribed for children under 3 years of age. The second medicine does not provide for age restrictions.

There is a difference in the composition and quantity of auxiliary components. But this does not affect the pharmaceutical properties of medicines.

The release of 5-NOC is carried out in Slovenia by the pharmaceutical company LEK. Nitroxolin is produced in Russia by various pharmaceutical companies.

Well, of course, there is a difference in the cost of the pills. Russian pills can be purchased at a pharmacy for 55-100 rubles. The medicine from Slovenia will cost 230-260 rubles.

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