Both pills and injections contain B6 vitamins. They belong to the same pharmacological group. Used in neurological practice. They require compliance with the dosage, otherwise they can lead to undesirable side effects.
Tablets are used for longer courses and are more expensive. Typically, injections are prescribed in the acute period, and then switch to tablets: 1/3 times a day.
A stroke kills more than 6,000,000 people annually . From epilepsy suffers – 50 million people. This process cannot be eradicated, but different combinations of drugs help to prevent or support during difficult times. Vitamin complexes play an important role. One of the most frequently prescribed by neurologists is Milgamma.
Although tablets and injection are common characteristics and are produced by the same manufacturer, there are differences:
- The composition of the tablets includes benfotiamine – this is an analogue of vitamin B1, and the injections contain vitamin B1 (thiamine).
- The composition of the injections contains cyanocobalamin B12 and lidocaine, which is not in the tablets. Therefore, they have a more pronounced analgesic property.
- Milgamma injections enter the bloodstream faster, bypassing the digestive tract, providing a therapeutic effect.
- The drug in tablets contains sucrose, which means it is prohibited for patients with fructose intolerance, which can not be said about injections.
- The injections contain benzyl alcohol, therefore, the children’s category of patients under 12 years of age is contraindicated.
The drug is available in the form of tablets and injections. To find out when and what is better to apply, you need to understand everything in more detail.
White tablets have a smooth surface through an enteric coating. 15 pieces are placed in the blister. Packing: 2 or 4 blisters.
Each unit contains 100 mg of a fat-soluble analogue of vitamin B1 ( benfotiamine ) and 100 mg of one form of vitamin B6 (pyridoxine hydrochloride). One of the additional components is sucrose.
Milgamma tablets are among the group of combined vitamins B1 with B6 / B12 and are classified as neurotropic vitamins of group B.
It has a positive effect on inflammation and degeneration of nerves and the motor system. Eliminates deficient conditions of the body without vitamins. At high doses, an analgesic effect is noted. This combination stabilizes the nervous system, improves the blood formation process, and enhances blood circulation.
The drug is easily absorbed in the digestive tract, excreted within 5 hours.
It is important to monitor the dosage of the drug used, since with an overdose, there may be: hypoactivity of liver enzymes, pain in the heart, hypercoagulation (increased blood coagulation activity), relaxation of skeletal muscles.
Vitamin B6 at a dose of ≥ 50 mg / day, for six months or more, will lead to peripheral sensory neuropathy (a disease of the nerves of the peripheral system, except for the spinal cord).
A dose of ≥ 1 g / day for 2 months is fraught with a neurotoxic effect (a change in the structure or chemistry of the nervous system).
Dose B1≥ 2g / day can cause a sensitivity disorder, ataxia, cerebral seizures. Hypochromic anemia and seborrheic dermatitis are not excluded.
First aid: gastric lavage, oral administration of activated carbon.
At the time of an overdose, the adverse reactions of Milgamma may intensify:
- GIT : increased acidity; pain, vomiting syndrome; nausea upset stool.
- CVS : heart palpitations.
- Immune system : hypersensitivity (anaphylaxis); rashes (urticaria).
- Skin : rashes accompanied by itching.
- CNS : nervous excitement, headache, dizziness.
- Endocrine system : increased prolactin.
Country producer Germany. Shelf life up to 5 years at a temperature of ≤ 25 ° C. It is released without a prescription.
Clear red injection. Placed in brown glass ampoules.
Each unit contains: 100 mg of thiamine hydrochloride (B1), 100 mg of pyridoxine hydrochloride (B6), 1 mg of cyanocobalamin (B12). One of the excipients is lidocaine (an analgesic) and benzyl alcohol.
The pharmacological action is carried out due to the selected combination of B vitamins. It has a neuroprotective, metabolic and analgesic effect on nerve tissues.
The main purpose of Milgamma for injection is nervousness and nervous-like conditions. The action of B1 / B6 extends to the nervous / neuromuscular system.
B12 inhibits pain in the affected areas of the peripheral nervous system by synthesizing the myelin sheath. Cyanocobalamin is involved in the formation of nucleic acids. Regulates biosynthesis between nerve endings and fibers. It is responsible for blood coagulation.
Through lidocaine, anesthetizing effect.
Along with a positive effect, the drug in injections can cause side effects:
- Often: allergic reactions, skin itching, urticaria.
- Rarely: increased sweating; palpitations, acne.
- Possible: hypersensitivity to the components, shortness of breath, anaphylactic shock.
Side effects may increase overdose. After stopping the administration of the drug and symptomatic treatment, the condition of the patients returns to normal.
To whom and when will this or that form of Milgamma fit?
Each of the forms of the drug is prescribed for neurological disorders caused by a lack of B vitamins. Provided that it is impossible to make up for it with a nutrition correction.
Injections are never prescribed for:
- Individual intolerance.
- Severe forms of cardiac conduction disturbance.
- Pregnancy and lactation, since 2 ml of the drug contains more than the permissible dose of pyridoxine hydrochloride, and it is able to penetrate into milk.
Do not use in the treatment of children under 12 years old. Elderly patients do not require special adjustments. Milgamma is administered exclusively intramuscularly, as deep as possible.
Tablets are prescribed with caution in patients with gastric and duodenal ulcers, renal and hepatic insufficiency. Contraindicated in patients with tumors, except megaloblastic anemia. Applied with angina pectoris and other acute decompensated cardiac forms of the disease.
Patients with paristhesia require dosage adjustment or cancellation of the appointment. It is important to remember that self-medication can be hazardous to health.