Buscopan or No-shpa, which is more effective

Usually, both drugs relieve pain associated with smooth muscle spasms. However, this does not always happen. If pain does not go away when taking this or that drug, then you should look for their cause elsewhere.

With the simultaneous administration of antispasmodics, they enhance their therapeutic effect.

Thus, both drugs are effective in eliminating pain. Despite the good tolerance of both, the choice should be made by a doctor based on the symptoms.

Many diseases of the internal organs are accompanied by pain. Often it is associated with spastic muscle contraction. Sometimes it is impossible to tolerate such pain and antispasmodics are used to eliminate it. Such means are Buskopan and No-shpa. They act on the smooth muscles of muscles and suppress impulses in the central nervous system. Due to this, the pain is eliminated quickly enough. Many patients are interested in which of the drugs is more effective. To give an answer, you need to study both drugs in more detail.


The active substance is hyoscine butyl bromide. It has an antispasmodic effect. Available in the form of tablets and candles.


The drug has an antispasmodic effect on the smooth muscles of the gastrointestinal tract, gall bladder and genitourinary organs. However, it does not have an anticholinergic effect on the nervous system.

An additional component is paracetamol. Due to this, Buscopan eliminates the pain syndrome, acting right at the place of its occurrence.

The active substance is slightly absorbed in the digestive tract. Bioavailability is only 8%. The maximum concentration of the drug is observed 2 hours after administration.

Indications are:

  1. Spasm in the genitourinary system and gastrointestinal tract.
  2. Exacerbation of peptic ulcer.
  3. Biliary dyskinesia and gall bladder.

Buscopan is prescribed to some patients before starting labor.

Despite the fact that there are no negative effects on the fetus, the drug is not prescribed in the early stages of pregnancy. In the future, the drug should be administered only under the supervision of a doctor.

Contraindications are:

  • Children under 6 years old.
  • Individual intolerance to the components.
  • Myasthenia gravis, glaucoma, pulmonary edema.

Suppositories are forbidden to use for prostate adenoma and heart failure. Tablets are taken in 1-2 pieces 3 times a day, drinking plenty of water.

Suppositories are for rectal use. 1-2 pieces 3 times a day. It is necessary to free them from the membrane and enter into the rectum. The duration of treatment is determined by the doctor.


The active substance is drotaverine. Available in the form of tablets and injection. It has an antispasmodic effect.


Drotaverinum is a myotropic antispasmodic. The action reduces the tone and motor activity of smooth muscles. Due to this, the blood vessels expand.

Since drotaverin acts on smooth muscles, pain can be relieved even when it is impossible to use anticholinergic drugs.

Bioavailability of 100%. In the digestive tract it is absorbed quite quickly. Maximum concentration after 45-60 minutes. The elimination half-life makes 8-10 hours. After 72 hours, the substance is completely excreted from the body.

Indications are:

  1. Spasm of smooth muscles with cholecystitis, cholangitis, papillitis and other diseases.
  2. Spasm of smooth muscles in diseases of the genitourinary system (cystitis, pyelitis and others).
  3. Toothache.
  4. Menstruation pain.

It is also used during the onset of pain in diseases of the stomach and intestines. Peptic ulcer, colitis, pyloric spasms are also indications for use. Also used for headaches.

It is advisable to take tablets to ensure a lasting effect, reducing the number of doses.

In ampoules of No-spa is necessary in the case when it is impossible to take pills. Indications are the same, as well as pancreatitis with indomitable vomiting.

Contraindications are:

  • Individual intolerance to the drug.
  • Renal and liver failure.
  • Low cardiac output syndrome.
  • Lactase deficiency.

With caution is prescribed for children, pregnant women and patients with low blood pressure.

What to choose?

The main difference between the drugs is the country of origin. Means have different active components. Buscopan is produced by a German pharmaceutical company, and No-shpa is produced by Russian. Hence the price difference. Buscopan costs about 400 rubles, while No-shpu can be purchased at a price of about 100 rubles. Both drugs are not recommended for use during pregnancy and breastfeeding.

The list of side effects is also slightly different, with drug intolerance. When taking Buscopan, an allergic reaction (in the form of a rash, trial, urticaria), dry mouth, respiratory failure, increased heart rate may occur. When taking No-shpa, a decrease in blood pressure, increased heart rate, headache, nausea, vomiting, and allergic reactions can be observed. If the drug was administered intramuscularly, then the manifestations will be at the injection site.

However, the drugs have a large number of similarities. Both of them have antispasmodic action, and also have the same list of indications.

Buscopan benefits are:

  1. Fast antispasmodic action.
  2. Does not complicate the diagnosis of surgical diseases.
  3. It does not affect the central nervous system.
  4. Good tolerance for prolonged use.
  5. Long-term healing effect.
  6. Effective and safe, as revealed by clinical trials.

No-shpa also has positive aspects:

  • Low price.
  • High bioavailability.
  • The presence of several dosage forms.
  • Minimum side effects.
  • The rapid onset of therapeutic action.
  • It does not affect the functioning of the liver.
  • It interacts well with other drugs.

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