Nise or Nurofen, which is more effective

It is impossible to say unequivocally which of the drugs is better. This can only be determined by a specialist, based on the characteristics of the patient.

Both drugs belong to the same pharmacological group. However, the active substance is different for them, as well as the mechanism of action. Nurofen helps with moderate pain and acts directly on the focus. Nise is able to eliminate strong and intense pain, however, he copes with inflammatory processes not so effectively.

Both drugs have a depressing effect on the gastrointestinal tract, so they can not be taken for a long time. Also, drugs can not be taken at the same time, as this can worsen the patient’s condition.

Unlike Nise, Nurofen has a large number of analogues available that are well tolerated by patients. Nurofen also has childhood forms, due to which the drug can be prescribed even to babies. Nise can only be used for children over 12 years old.

In all cases of toothache, Nurofen is most effective. And if it’s easy for adults to find a replacement, then teething children save syrup and suppositories.

Nise effectively copes with symptoms of joint diseases. When it is taken, morning stiffness and pain are reduced.

From this we can conclude that with intense pain it is better to use Nise. With moderate pain, as well as children, Nurofen is suitable.

Thus, it is not possible to say specifically which drug is better. Everyone has positive and negative points. The choice of drug should be carried out by the doctor individually for each patient, based on the clinical picture. Do not self-medicate, as long-term use of non-steroidal anti-inflammatory drugs can lead to a deterioration in the patient’s condition.

Nonsteroidal anti-inflammatory drugs. Used to eliminate pain and reduce temperature. Assigned to both children and adults. Some patients wonder which drug is best. To give an answer, you need to consider in detail both drugs.


The active substance is nimesulide. Available in the form of tablets and gel. It has anti-inflammatory, antipyretic and analgesic effects. Anesthetic effect is observed 15 minutes after administration. The maximum concentration of a substance in blood plasma is observed after 30 minutes.


The drug is able to inhibit the formation of enzymes that destroy cartilage. Also reduces histamine release and eliminates bronchospasm. Therefore, it can be used for bronchial asthma.

The maximum concentration of the drug in the body is observed after 2 hours. It penetrates well into tissues and body fluids. When applying the gel, the components penetrate well into muscle and joint tissue. It is found in blood in small doses. The therapeutic effect is observed after 4 weeks of regular use.
Indications for use of tablets:

  • Arthritis.
  • Osteoarthrosis.
  • Osteochondrosis.
  • Thrombophlebitis.
  • Toothache and headache.
  • Fever

Indications for use of the gel:

  1. Rheumatoid and psoriatic arthritis.
  2. Osteochondrosis.
  3. Lumbago syndrome.
  4. Bursitis.
  5. Sciatica.
  6. Sprain and bruises.

Contraindications are:

  • Exacerbation of peptic ulcer.
  • An allergic reaction to the components of the drug.
  • Pregnancy and lactation.
  • Children under 12 years old.
  • Hepatic and renal failure.

Caution should be taken with diabetes with hypertension and lupus erythematosus. After taking the tablets, drowsiness is observed , so you should refrain from driving a vehicle.

Adults and children over 12 years of age are recommended to take 2 tablets a day. It is better to take before meals with water. When discomfort occurs, tablets are taken at the end of a meal. The maximum dose per day is 400 mg. In case of impaired renal function, the dose decreases. If, when taking pills, symptoms associated with impaired liver function appear, then the drug is canceled. After a two-week intake, it is necessary to do a biochemical blood test to check liver function indicators.

The gel has a pronounced analgesic effect. It is applied to a painful place 2-3 times a day, with a thin layer, it is not rubbed. The amount of gel may vary depending on the size of the affected area. Do not apply under dressings or on areas with damaged skin.


The active substance is ibuprofen. Available in the form of tablets and gel. There are also syrup and suppositories for children. It has anti-inflammatory and analgesic effects. To a lesser extent, an antipyretic effect is observed. The substance is absorbed into the body after 30-60 minutes. Penetrates into the synovial tissue, but does not penetrate into the joint cavity. Most are excreted by the kidneys, the rest through the intestines.


Indications are:

  • Joint diseases.
  • Pain syndrome.
  • Fever.
  • Toothache, headache and migraine.

The gel is recommended for use with:

  1. Back pain.
  2. Myalgia and neuralgia.
  3. Injuries (bruises and sprains).
  4. Arthritis.

For children’s syrups and suppositories, the indications are the same. In addition, children are allowed to use for acute respiratory infections, flu, childhood infections and vaccine reactions.

Contraindications are:

  • Gastrointestinal ulcers and bleeding.
  • Heart failure.
  • Hypertonic disease.
  • Individual intolerance to the components of the drug.
  • Violations of the liver and kidneys.
  • Hemophilia.
  • Intracranial hemorrhage.
  • Pregnancy and lactation.

Adults and children over 12 years of age are prescribed 1 tablet 3-4 times a day after meals. The gel is applied 4 times a day. It is applied to the affected area with a thin layer and rub well into the skin. The interval between applications should be at least 4 hours.

The dosage of syrup for children is calculated from the formula 5-10 ml per 1 kg of body weight. As an antipyretic, it is taken no more than three days, and as an anesthetic – no more than five. Suppositories are administered rectally, 3-4 times a day, one at a time.

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