Sumamed is a broad – spectrum antibiotic belonging to the macrolides group (ozalid). He is appointed in a number of pathologies of infectious origin.
Current component and dosage forms Sumamed
The drug is made by the Croatian pharmaceutical company in the form of capsules, tablets and powder for preparing suspension. Current active component is azithromycin (in the form of dihydrate).
In 1 tab. there is 125 or 500 g of azithromycin. They come in the pharmacy network of 3 or 6 pieces.
1 capsule contains 250 mg azithromycin. They are sold in blister of 6 PCs.
Sumamed can also be purchased in powder form, Packed in 17 vials of dark glass. The kit includes 5 ml dosing syringe or the special bilateral spoon to measure 2.5 or 5 ml of medicine.
Macrolide-azalide wide action spectrum has a pronounced bacteriostatic action against a variety of pathogenic microorganisms. Azithromycin inhibits protein synthesis of bacteria, preventing growth and reproduction of their colonies. In high doses, it has a bactericidal effect.
Sumamed particularly effective to suppress the reproduction of the threat of gram-positive bacteria, including Staphylococcus aureus, and gram-positive aerobes may have developed resistance to azithromycin or to quickly develop resistance to the drugs.
After administration per os antibiotic-macrolide quickly and almost fully absorbed and distributed in organs and tissues. The maximum concentration in plasma is recorded after 2-3 h. the Level of bioavailability is approximately 37%. Sumamed penetrates through the cell walls (membranes) and transported by phagocytes to the area of introduction of the infection. There he aktiviziruyutsya in the presence of pathogenic microorganisms.
It is important
Concentrations in infectious foci by 30-35% higher than in healthy tissues.
Biotransformatia takes place in the liver. BOS loses activity due to demethylation. The half-life is the rate of from 35 to 50 hours. Even after 5-7 days after the course is maintained therapeutic concentration of the macrolide. Sumamed excreted mainly through the intestines in nematerializiranih.
Testimony to start taking Sumamed
Antibiotic indicated for pathologies of infectious-inflammatory origin, caused by sensitive to azithromycin microorganisms.
It is recommended for the following diseases:
Among the contraindications include: individual intolerance of azithromycin and other macrolides, as well as severe liver dysfunction and (or) kidney.
Dosage and mode of admission Sumamed
Antibiotic designate 1 p/day 1 hour before meal or 2 hours after a meal. Capsules and tablets should not be chewed and crushed; swallow whole with sufficient quantity (50-100 ml) of boiled water.
Children under 12 years of age (weighing ≥ 45 kg) and adult patients Sumamed assigned in the form of capsules or tablets.
The kids, starting with six-month of age, azithromycin is given in the form of a slurry with a characteristic strawberry odor. Children from 3 years drugs can be given in the form of tablets, 125 mg.
Dosing for young patients is determined by calculating:
- 18-30 kg body weight – 250 mg (2 tab.);
- 31-44 kg – 375 g (3 tab.);
- ≥ 45 kg – adult dose (determined by the treating physician).
To prepare the suspension, the factory bottle (17 g) was injected 12 ml of water for injection (you can use plain boiled water). The total amount of drug should be 23 ml. Prepared suspension cannot be stored longer than 5 days. Before you give antibiotic to a child tightly closed the bottle is thoroughly shaken to obtain a homogeneous substance.
If the child weighs more than 13 kg, you should take instead of the usual “Sumamed” (100 mg azithromycin/5 ml) “Sumamed Forte” (200 mg/5 ml).
At pathologies of gastrointestinal tract, associated with Helicobacter pylori, 1 is assigned to g Sumamed a day in combination with other antibacterial drugs and a proton pump inhibitors. The duration of a course of treatment – 3 days.
Acne (acne) moderate severity requires admission 6 g per course (for adults and children over 12 years). 3 day drink 500 mg daily, then 500 mg with a week off for the 9 months.
Infections of the genitourinary and reproductive system are shown a single dose of 1 g Sumamed. If urethritis or cervicitis is characterized by long protracted due to chlamydia, azithromycin you need to take 1 year with weekly intervals. The total dose rate – 3 g.
Azithromycin rarely causes side effects. Intolerance to the active substance or additives is not excluded allergic reactions.
Probable side effects:
Information about drug overdose Sumamed were reported. Theoretically, it is possible the hearing loss, vomiting and bowel disorders (diarrhea). The victim shown symptomatic therapy.
Combination with other pharmacological agents
This antibiotic is strictly forbidden to take concurrently with ergotamine and dihydroergotamine. It is extremely desirable to combine the macrolide with warfarin (requires control of prothrombin time), terfenadine (it is possible arrhythmia), and digoxin (its absorption in the intestine increases).
It is also not recommended to take astemizole, quinidine, cisapride, pimozide and medicines containing ergot alkaloids.
Sumamed during pregnancy and lactation
In the period of gestation an antibiotic is possible only on prescription.
During breastfeeding Sumamed not assigned. If necessary, treatment of nursing mother of the child is transferred to the artificial mixture.
Treatment with antibiotics due to the inevitable dysbiosis can cause accession superinfection.
It is important
The progression of the prostate causes a frequent urge to urinate, pain in the area of the perineum and lower abdomen and General lethargy and apathy. The development of pathogenic bacteria in the prostate gland possible on the background of violations of the outflow of lymph, so many experts prescribe Sumamed for increase of efficiency of treatment of inflammation of the prostate.
Azithromycin is practically ineffective for the prevention of acute rheumatic fever.
Sumamed can cause dizziness, so during the course of treatment, it is advisable to refrain from work requiring high concentration.
Sumamed and alcohol are absolutely incompatible. At the same time strictly forbidden to take Sumamed and drinks containing ethyl alcohol (including pharmacy tincture).
If you accidentally skipped the next dose, it should be taken as soon as possible. In the future, the drug is carried out according to prescribed scheme.
Rules of storage and sale through pharmacies
Sumamed listed in “list B” (powerful drugs, so its purchase will need a prescription.
Vials and blister packs should be stored at a temperature in the range from +15° to +25°C.
Shelf life for tablets and capsules is 3 years and for powder 2 years from the date of issue specified on the original packaging.
Keep away from children!
Analogues to the active component and the therapeutic effect are the following drugs:
- Flemoksin Soljutab;
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