Yarina or Diane-35, which is more effective

Both drugs are quite effective as a contraceptive. However, the selection of the drug should still be carried out by a gynecologist individually for each girl.

The main difference in the preparations is their composition. Also, the difference is that Diane-35 eliminates the symptoms of androgenization.

The price of drugs is almost the same. The cost for 21 tablets of both drugs is in the region of 1100 rubles.

The benefits of taking Yarina are:

  1. Suppression of male hormones in the body.
  2. The soreness during menstruation is reduced.
  3. It does not affect body weight.
  4. It does not contribute to the accumulation of fluid in the body, which eliminates the development of edema.
  5. Even if the egg enters the uterine cavity, then it is not mature enough for fertilization.

Also, Diana-35 has a number of advantages:

  • The menstrual cycle normalizes, pain decreases.
  • Symptoms of androgenization are reduced (unwanted hair growth, sebum production).
  • High bioavailability.
  • The possibility of treating infertility, polycystic ovary and other gynecological diseases.
  • Reducing the manifestations of mild forms of hirsutism in women of reproductive age.

Many women who have tried both drugs prefer Yarina. According to their reviews, when using Diane-35, side effects in the form of nausea, dizziness and weakness were often observed.

Thus, it is impossible to say unequivocally which of the drugs is better. As oral contraceptives, they are both effective. However, the drug should be selected by a doctor based on the individual characteristics of the woman and her body condition. It is also important to remember that skipping pills is undesirable, as this does not guarantee complete protection against pregnancy.

To prevent unwanted pregnancy and treat certain diseases, doctors often prescribe oral contraceptives. They contain two types of hormones – estrogens and progestins. Taking such drugs is the most common way of preservation in many countries. The same group includes drugs Yarina and Diane-35. Often in women, the question arises which of these oral contraceptives is better. To understand this, you need to consider each of the drugs.


Active substances are 3 mg of drospirenone and 30 μg of ethinyl estradiol. The action is carried out by blocking ovulation and increasing the viscosity of mucus in the fallopian tubes.

In women and girls using this drug, the menstrual cycle normalizes, menstruation becomes less painful and decreases in volume. This reduces the likelihood of developing iron deficiency anemia.


Drospirenone is rapidly absorbed after administration. The maximum concentration of the drug in the blood is observed 1.5 hours after administration. Bioavailability is 75-85%, food intake does not affect it.

Ethinyl estradiol is also actively absorbed after administration, and the concentration reaches its maximum after 1.5 hours. Bioavailability is about 45%. The elimination half-life is 24 hours. It is excreted in urine and bile.

The main indication for the use of the drug is the prevention of unwanted pregnancy.

Contraindications are:

  • Thrombosis and thromboembolism.
  • Pancreatitis
  • Migraine.
  • Diabetes.
  • Renal failure.
  • Disorders of the liver.
  • Tumors of the liver.
  • Hormone-dependent malignant neoplasms.
  • Individual intolerance to the components.
  • Vaginal bleeding of unknown origin.
  • Lactation, pregnancy or suspicion of it.
The drug is taken for 3 weeks, 1 tablet per day, at about the same time. After the end of the pack, you need to take a seven-day break. At this time, “withdrawal bleeding” begins. Usually 3-4 days after discontinuation of the drug. On the eighth day, you should start taking a new pack, regardless of whether the menstruation has ended or not.

When skipping a pill, you need to take it within 12 hours. You can also take 2 tablets the next day at a time.

If prior to this, oral contraceptives have not been taken, then the first tablet should be drunk on the first day of menstruation.

Diana 35

The active substance is cyproterone acetate 2 mg and ethinyl estradiol 35 μg. It has antiandrogenic, estrogenic, contraceptive and gestagenic effects. Due to hormones, the viscosity of the mucus increases, which makes it difficult for the sperm to enter the uterine cavity. The severity of the manifestations of androgenization in women is reduced. Decreased sebum production, hair loss and unwanted hair growth. The severity of acne is also reduced.

Diana 35

When taking a contraceptive, the menstrual cycle normalizes, soreness during menstruation decreases, the discharge becomes less intense.

The maximum concentration of cyproterone acetate is observed 1.5 hours after administration. Bioavailability 88%. The elimination half-life is 2-3 hours.

Ethinyl estradiol is rapidly absorbed into the blood, and the highest concentration is observed after 1.5 hours. Bioavailability of 45%. The elimination half-life is 1-3 hours.

Indications are:

  1. Prevention of pregnancy.
  2. Symptoms of androgenization (seborrhea, acne, alopecia).
  3. Diseases of the female reproductive system (including polycystic ovary).

Contraindications are:

  • Intolerance to the components.
  • Lactation, pregnancy or suspicion of it.
  • Itchy skin or idiopathic jaundice.
  • Thrombosis.
  • Angina pectoris.
  • Endometrial or breast cancer.
  • Otosclerosis.
  • Diabetes.
  • Vaginal bleeding of unknown origin.
  • Hormone-dependent neoplasms.

Admission is 1 tablet per day for 3 weeks. Next is a seven-day break in which menstruation begins. On the eighth day, after cancellation, it is necessary to start receiving a new pack. If you skip, the tablet should be taken no later than 12 hours, otherwise the contraceptive effect of the drug will decrease.

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