Eating plenty of fish protects against sight loss

Omega-3 oils ‘precondition’ cells in the eye to withstand ‘stress’, such as a loss of blood supply, according to researchers.

Eating plenty of salmon, sardines and mackerel may protect against sight loss, new research reveals.

A chemical in oily fish boosts the survival of cells that are critical to vision, protecting against age-related sight decline, a US study found.

In laboratory tests, human eye cells exposed to constant light withstand damage if they are supplemented with such oils, the research adds.

Vision loss affects almost two million people in the UK. The leading cause is age-related macula degeneration (AMD) which has 600,000 sufferers.

Eating plenty of salmon, sardines and mackerel may protect against sight loss, research shows


In 2015, more than two million people in the UK were living with sight loss. This affects one in five people over 75, particularly women.

At least 50 per cent of cases could be avoidable if the sufferer was fitted with the correct prescription glasses or underwent cataract surgery. Older people with sight loss are almost three times as likely to suffer depression.

Almost half of partially or totally blind people feel ‘moderately’ or ‘completely’ cut off from others. Blindness rates are set to increase dramatically as the population gets older and illnesses that boost the risk of sight loss, such as diabetes, rise.

Omega-3 is necessary for ‘preconditioning protection’

Results reveal the omega-3 fatty acid DHA, which is abundant in oily fish, ‘preconditions’ different types of retinal cells to be able to withstand ‘stress’, such as their blood supply being cut off.

The retina is a thin layer of tissue that lines the back of the inner eye. It converts light into signals, which are sent to the brain where they are interpreted to provide vision.

Retina damage leads to the degeneration of the macula, which is responsible for what we see directly in front of us and therefore plays a critical role in reading, writing and viewing colour.

Although fish oil also contains omega-6 AA, which is inflammatory and could therefore cause damage, omega-3 DHA is thought to alter the former oil’s action.

In laboratory experiments the researchers exposed human retinal cells, as well as those of living rats, to constant light. Prior omega-3 DHA supplementation saved these cells from destruction.

Lead author Professor Nicolas Bazan from Louisiana State University, said: ‘Our findings demonstrate DHA is necessary for preconditioning protection.’

The discovery, published in the journal Cellular and Molecular Neurobiology, could lead to new treatments for a host of degenerative diseases of the retina.

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