Clotrimazole or Exoderil, drug choice

Despite the effectiveness in treatment, the agents have differences among themselves, as well as their positive and negative sides.

“Exoderil” is safer to use, since it does not accumulate in the liver and is rapidly excreted from the body. The greatest efficiency is achieved in the treatment of mold. It relieves the sensation of itching well.

The effectiveness of treatment is achieved by rapid absorption of the active substance with subsequent accumulation, therefore, the therapeutic effect after application lasts a long time. The drug can be actively used for the treatment of fungal diseases, their prevention (which is especially important for people who often visit public baths, saunas, pools, gyms, etc.).

The tool not only fights the disease, but also slows down its development and prevents it from appearing with prophylactic use. It is important to remember that treatment will be effective only with prolonged use of the drug – until a healthy nail is fully grown.

Exoderil can only be used on skin and nails.

“Clotrimazole”, in turn, perfectly treats nail and foot fungus, lichen, including is often used to get rid of vaginal troubles. On average, Clotrimazole is treated for about a month. After treatment, the use of the drug can be continued for prevention. It is used not only externally, but also intravaginally, since the drug actively fights local female foci of infections, inflammation and fungal diseases. “Clotrimazole” can be used to treat not only the skin and nails, but also the mucous membranes (oral cavity, vagina, etc.), which makes the drug a multifunctional more versatile tool in the fight against bacteria and fungi.

The drug is not so harmless, as it penetrates the bloodstream and can thereby affect every cell in the body.

Fungal diseases cause a lot of trouble to a person. When the first signs appear, a person tries to find an effective medicine for recovery as soon as possible. However, this is not always easy to do: drugstore shelves are bursting with an abundance of creams, ointments and gels, candles, and it is not easy to understand them. For example, dermatologists often advise their patients to purchase Clotrimazole or Exoderil. What is the difference between them, how effective and equally good are they in treating the same diseases?


The main function of the drug is the treatment of fungal diseases. It is applied topically. It has antibacterial, antiprotozoal, trichomonacid, antifungal effects. It is effective in controlling a wide range of microorganisms.


The effect of the drug is achieved by a violation of the synthesis of ergosterol : the membrane of the fungal cells becomes thinner and becomes permeable. As a result, potassium, phosphorus is eliminated from fungal cells, nucleic acids decompose. Further, oxidative and peroxidase enzymes cease to work actively, because toxins are accumulated in the cells of the fungus in such an amount that the cellular organelles simply collapse, and the cell itself dies.

First of all, the product actively fights against growing or multiplying bacteria. It can be used to treat diseases caused by dermatomycetes, as well as candidiasis, lichen multicolor, erythrasma, staphylococci, streptococci, gram-negative bacteria, trichomoniasis.

Only in exceptional cases are there varieties of fungi that are resistant to this drug. Primary resistance can be encountered with candidiasis.

The drug is hardly absorbed into the skin and mucous membranes. It tends to accumulate in dead skin cells. May be in keratin when applied to nail plates.

With intravaginal administration, no more than 10 percent of a single dose is absorbed.

The drug is easily and quickly excreted by the liver through feces. The drug is stored in the blood and vaginal secretions up to three days after application.

The tool can cause an allergic reaction in the form of itching and rash. Burning sensations, vaginal discharge, frequent urination, cystitis, soreness during sexual intercourse, redness in the oral cavity (when used in the oral cavity), burning, tingling, and irritation may also occur.

With an overdose of the drug, hallucinations, nausea before vomiting, gastralgia, improper functioning of the liver are possible, sometimes a feeling of drowsiness, hallucinations, an allergic rash.


The drug effectively fights fungi, has a disinfecting effect and inhibits the growth of fungi. The tool acts on the walls of the fungal cells, thinning them. The tool is effective in the treatment of diseases caused by dermatophytes (microsporum, epidermophyton, trichophyton), mold, yeast (such as Candida) and other mushrooms. Exoderil also acts on bacteria that can cause secondary bacterial infection. The anti-inflammatory effect of the drug quickly helps get rid of itching and signs of inflammation.


The tool is able to be rapidly absorbed into the skin in high concentrations, which ensures its long-term effect on the causative agent of the disease in different layers of the epidermis. Therefore, it can be used only once a day.

The drug is indicated for:

  • Fungal skin lesions.
  • Interdigital mycoses.
  • Fungal lesions of the nail plates.
  • Cutaneous candidiasis.
  • Pityriasis versicolor.
  • Dermatomycosis.

You can not use the drug for allergies to the components of the drug, pregnancy, breastfeeding. In rare cases, the drug can be used in children, but to a limited extent. In no case should the product be applied to damaged skin.

A side effect can occur in the form of dry skin, hyperemia, a burning sensation. There is no need to cancel the drug, since all the symptoms will disappear after the end of the course of treatment.

What is common between means?

Both drugs effectively fight fungal diseases. The use of both drugs is local, therefore, oral administration is not required.

The agents are partly similar in their effect on the fungus – the active substances of the drug thin the cell wall, making it permeable and thereby damaging the fungus.

Both drugs can be used for mycoses, candidiasis, lichen, inflammatory processes.

When and what should be applied?

Indications for use of “Clotrimazole”:

  1. Fungal diseases of the skin, mucous membranes.
  2. Complicated mycosis.
  3. Multi-colored lichen, erythrasma.
  4. Stomatitis caused by Candida bacteria.
  5. Vulvitis caused by Candida bacteria. vulvovaginitis, trichomoniasis, balanitis.
  6. Sanitation of the mucous membranes before childbirth.

It is contraindicated in case of allergies to the components of the drug.

Application during pregnancy is possible, but undesirable. It is not known whether it is possible to take the drug during breastfeeding, since no studies clarifying this situation have been conducted. This tool is able to penetrate the blood and spread to all organs of a person, therefore it can not be used by children under the age of thirteen, as well as people with impaired renal and hepatic function.

It is not used for menstruation (if necessary, intravaginal administration).

Exoderil is used in cases:

  • Fungal diseases.
  • Mycosis of the skin and nails.
  • Candidiasis on the skin.
  • Cutaneous candidiasis.
  • Some types of lichen.

It can not be used for allergies to the components of the product, pregnancy, breastfeeding. In rare cases, the drug can be used by children, but to a limited extent and under the supervision of a doctor. The drug is by no means applied to damaged skin.

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