The most important difference between these forms is the route of administration and the concentration of the active substance. Lyophilisate contains 5 mg of prostate extract, and candles 50 mg. It is difficult to deliver injections without professional skills at home. Therefore, the lyophilisate is administered mainly in hospitals or in clinics. Suppositories are administered rectally and are easier to administer at home. The candles are moistened with water, and after the introduction, the patient must be in a horizontal position for up to 40 minutes. Unforeseen allergic reactions from injections are also much more common. When they occur, treatment is stopped and antihistamines are prescribed. There are no contraindications for the use of both forms.
In storage conditions there are also differences. Suppositories are stored at room temperature, but the lyophilisate can only be stored in a refrigerator from 2 to 15 degrees. Suppositories can be purchased without a prescription in any pharmacy, while the lyophilisate is sold exclusively by prescription.
Men with prostatitis are faced quite often. This disease refers to urological diseases. Depending on the type of prostatitis, it is divided into acute and chronic. Acute develops when pathogenic microbes enter the prostate gland. Sexually transmitted infections contribute to it. But they do not always contribute to the penetration of prostate tissue. If blood circulation in the pelvic region, poor lymph outflow, hormonal imbalance are disturbed, microbial cells easily penetrate the prostate. The chronic course of the disease is affected by a decrease in immunity, hypothermia, prolonged abstinence from sexual intercourse, or vice versa an excessive, inactive lifestyle and other factors.
A man experiences pain in the groin and scrotum. There is a urge to urinate frequently with cuts in the urethra. As a result, the quality of life is deteriorating sharply. Such a drug as Prostatilen has long been known on the pharmaceutical market . This drug is very well established in the market, and has been widely used since 2006. It has two forms of release:
- Rectal suppositories.
- Lyophilisate for solution for intramuscular administration.
Consider two forms of release, and try to determine to whom and in what cases one form or another is acceptable.
Prostatilen in the form of suppositories
The active substance of this drug is prostate extract. It is an extract from the tissue of gobies. In this case, the bulls must reach puberty. This substance is a polypeptide structure. The extract acts selectively on the prostate gland and the genitourinary system as a whole.
Eliminates the inflammatory process by them
It is in that part of the prostate where the violation takes place. Prostatilen treat the chronic form of prostatitis. It reduces swelling, reduces the number of leukocytes in the prostate gland, and normalizes the secretory function of cells.
It perfectly stimulates the muscle tone of the bladder and normalizes urination. Due to this, pain also passes. It also prevents the development of vein thrombosis in the prostate gland. It is compatible with antibacterial drugs, therefore it is used in the treatment of acute prostatitis.
Prostatilene in the form of lyophilisate
Lyophilisate for solution for injection also contains prostate extract. Before administration, it is dissolved in 2 ml of an isotonic solution of sodium chloride, or in a 0.25-0.5% solution of procaine (a local anesthetic). When administered intramuscularly, the drug reaches a pronounced effect already at the third injection.
General characteristics of these release forms
In their composition, both forms contain an auxiliary substance glycine. It is part of many proteins and is a neurotransmitter acid. Glycine improves the transport and penetration of prostate extract into the prostate gland. Indications are the same for use in suppositories and lyophilisate. They are used both for treatment and for prevention after surgical interventions on the prostate gland. The convenience of introducing suppositories and injections only once a day, greatly facilitates the treatment of patients.
To whom and when it is better to apply this or that form of release
Candles are not administered to patients suffering from diseases of the rectum, including malignant tumors. With exacerbated hemorrhoids, they are administered with caution and only after consulting a proctologist or urologist. Men under 18 years of age do not administer this drug. Women are not prescribed the drug.
The drug has excellent characteristics in the treatment of abacterial prostatitis and benign prostatic hyperplasia. If prostatitis has developed against the background of a bacterial infection, then additional antibiotic therapy cannot be dispensed with. The drug does not have bactericidal activity. With male infertility associated with inflammation in the prostate gland, Prostatilen showed a good result. In addition to eliminating inflammation, it has a beneficial effect on sperm quality and sperm count rises. One course of treatment in 10-15 days is not enough, because the course is repeated after 1-6 months.
Prostatilen is one of the most prescribed drugs by urologists. It has a high evidence base and high safety in use. Even if the drug is relatively safe, it should not be used without a doctor’s prescription. Accurate diagnosis ensures proper treatment.